Results 41 to 50 of about 666,236 (309)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Method of Calculating Life-Cycle Fatigue Damage of Orthotropic Steel Bridge Decks under the Combined Actions of Vehicle Loads and Pavement Temperature

open access: yesShock and Vibration, 2020
The fatigue analysis on orthotropic steel bridge decks is a hot topic in bridge engineering field. This study provides one method for fatigue analysis under the combined actions of vehicle loads and pavement temperature.
Gaoxin Wang   +3 more
doaj   +1 more source

Large-bore tapered-roller bearing performance and endurance to 2.4 million DN [PDF]

open access: yes, 1983
The operating characteristics and experimental life estimates for 120.65 mm bore tapered roller bearings of two designs under combined radial and thrust loads were determined. A modified standard bearing design was tested at speeds up to 15,000 rpm.
Parker, R. J.
core   +1 more source

Identification of Critical Source Areas (CSAs) and Evaluation of Best Management Practices (BMPs) in Controlling Eutrophication in the Dez River Basin [PDF]

open access: yes, 2019
Best Management Practices (BMPs) are commonly used to control pollution in the river basins. Prioritization of BMPs helps improve the efficiency and effectiveness of pollution reduction, especially in Critical Source Areas (CSAs) that produce the highest
Ahmad, Sajjad   +3 more
core   +2 more sources

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

Model Test Study on Bearing Performance of Squeezed Branch Pile Under Combined Loads

open access: yesBuildings
This study investigates the mechanical performance of squeezed branch piles under combined loads (horizontal combined with uplift/compression) in silty clay through model tests.
Tian Deng, Kun Peng, Hong Li, Zhaoji Hu
doaj   +1 more source

Plastic collapse of pipe bends under combined internal pressure and in-plane bending [PDF]

open access: yes, 2005
Plastic collapse of pipe bends with attached straight pipes under combined internal pressure and in-plane closing moment is investigated by elastic–plastic finite element analysis.
Li, H., Mackenzie, D., Robertson, A.C.
core   +1 more source

The Relationship Between Acute: Chronic Workload Ratios and Injury Risk in Sports: A Systematic Review [PDF]

open access: yes, 2020
Purpose: Low injury rates have previously been correlated with sporting team success, highlighting the importance of injury prevention programs. Recent methods, such as acute:chronic workload ratios (ACWR) have been developed in an attempt to predict and
Canetti, Elisa   +3 more
core   +1 more source

Feasibility and Preliminary Efficacy of Integrative Neuromuscular Training for Childhood Cancer Survivors: A Pilot Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian   +7 more
wiley   +1 more source

Dynamic Stiffness Characteristics of Bearings Under Combined Loads with Rotor Excitation

open access: yesLubricants
The unbalanced excitation of a rotor has a significant impact on the dynamic stiffness of the bearing. Traditional unbalanced excitation force models for the calculation of bearing stiffness are usually simplified as single-directional excitation models,
Wei Dou   +4 more
doaj   +1 more source

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