Results 121 to 130 of about 3,352,860 (301)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

pyRoCS: A Python package to evaluate the resilience of complex systems

SoftwareX
This paper introduces pyRoCS, an open source Python-based software that enables users to quantify resilience of complex systems. The metrics used to quantify resilience are sourced from peer-reviewed publications across multiple domains, including ...
Amanda Wachtel, Thushara Gunda, Susan Caskey, Ryan Cooper, Thomas Womack, Kirk Bonney, Kenneth Kliesner   +6 more
doaj   +1 more source

Gaussian Combined Distance: A Generic Metric for Object Detection

IEEE Geoscience and Remote Sensing Letters
This paper is accepted by the GRSL in ...
Ziqian Guan, Xieyi Fu, Pengjun Huang, Hengyuan Zhang, Hubin Du, Yongtao Liu, Yinglin Wang, Qang Ma   +7 more
openaire   +3 more sources

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Casablanca conference, January 1943: papers and minutes of meetings.

, 2002
The minutes of the Combined Chiefs' meeting at the major conferences touch on virtually every policy and strategy issue of World War II, from initial troop deployments to counter Axis aggression, through the debates about the location and timing of the ...
Office, U.S. Secretary, Office of the Combined Chiefs of Staff
core  

Metrics for Quality Assurance of Web based Applications [PDF]

, 2015
Web-Commerce applications are now an indispensable aspect of businesses around the world. More businesses are now migrating from outdated applications to a new type of combined ebusiness designs.
Qasim Zia
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Association of the combination of obstructive sleep apnea risk and sleep duration with ideal cardiovascular health metrics in patients undergoing hemodialysis

BMC Nephrology
Background The purpose of this study was to explore the separate and combined associations of obstructive sleep apnea (OSA) risk and sleep duration with ideal cardiovascular health metrics in hemodialysis (HD) patients.
Hui Zhang, Ziwei Zhang, Yinjiao Zhao, Peiyu Song, Xiaoyu Chen, Peipei Han, Wei Ding, Liming Zhang, Chen Yu, Huizhi Ma, Qi Guo   +10 more
doaj   +1 more source

Upfront boost to gross disease followed by elective pelvic radiation improves compliance to radiation therapy delivery metrics in locally advanced vulvar cancer

Gynecologic Oncology Reports
Locally advanced cancer of the vulva (LACV) is commonly diagnosed in older women (>65 years), and is treated using combined multimodality therapy (CMT) that includes radiation therapy (RT).
M. Chadha, T. Shao, M. Lit, V. Gupta, K. Zakashansky, K. Zeligs, V. Kolev   +6 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source