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Current Opinion in Oncology, 1991
Encouraging results continue to emerge with the use of chemoradiotherapy. This review of the current literature demonstrates some of the advances that have been achieved in a variety of common malignancies with strategies based on well-defined rationales.
Timothy J. Kinsella, Cornelius J. McGinn
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Encouraging results continue to emerge with the use of chemoradiotherapy. This review of the current literature demonstrates some of the advances that have been achieved in a variety of common malignancies with strategies based on well-defined rationales.
Timothy J. Kinsella, Cornelius J. McGinn
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Combined modality therapy of esthesioneuroblastoma
Otolaryngology–Head and Neck Surgery, 2007ObjectiveEsthesioneuroblastoma (ENB) is a rare tumor of the olfactory epithelium. The objective of this study was to evaluate treatment modalities including surgery, IMRT, and chemotherapy and patient outcomes.Patients and MethodsA retrospective analysis was performed on a total of 21 patients.
Susan Muller +5 more
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Combined Modality Therapy for Rectal Cancer
The Cancer Journal, 2010The standard adjuvant treatment for cT3 and/or N+ rectal cancer is preoperative chemoradiation. However, there are many controversies regarding this approach. These include the role of short course radiation, whether postoperative adjuvant chemotherapy necessary for all patients and whether the type of surgery after chemoradiation should be based on ...
Minsky, Bd +2 more
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Combined Modality Therapy of Gastric Cancer
Surgical Oncology Clinics of North America, 1997Most patients with adenocarcinoma of the stomach continue to present with advanced stages of disease. Although cure is not possible without complete resection, most patients will go on to recur and die of their disease. Despite the efforts of the last 3 to 4 decades, little progress has been made in improving disease specific survival.
David P. Kelsen, Martin S. Karpeh
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Combined modality therapy of esophageal carcinoma
Cancer, 1981One hundred ten patients with epidermoid carcinoma of the esophagus were treated at the Memorial Sloan-Kettering Cancer Center (MSKCC) with combined modality techniques involving preoperative irradiation (RT) and surgery, and with preoperative chemotherapy (CT), surgery, and irradiation.
Patricia M. McCormack +7 more
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Combined modality therapy for esophageal cancer
Current Oncology Reports, 1999Whereas many patients with esophageal carcinoma present with what appears to be localized disease, cure rates with surgical resection alone remain low. Although surgical resection, where feasible, affords patients the best chance of cure, the primary tumor has often invaded local tissues or structures, and occult micrometastases often exist at the time
Mark J. Krasna, Ziv Gamliel
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Combined modality therapy for gynecologic cancer
Current Opinion in Oncology, 1995The use of combined modality therapy in the primary management of gynecologic cancer continues to be explored. Although early ovarian cancer is treated with postoperative adjuvant treatment, the data to support its value is lacking. In advanced disease, paclitaxel has emerged as the most optimal treatment after maximal cytoreduction.
Gillian Thomas, Ida Ackerman
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2014
Radiation therapy can be modified by increasing the effectiveness of radiation on tumors (radiosensitizers), protecting normal tissues (radioprotectors), increasing oxygen concentration, or by using systemic therapy drugs. Radio-protectors are described by their dose reduction factor (DRF) while radio-sensitizers are described by their enhancement ...
Foster D. Lasley +4 more
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Radiation therapy can be modified by increasing the effectiveness of radiation on tumors (radiosensitizers), protecting normal tissues (radioprotectors), increasing oxygen concentration, or by using systemic therapy drugs. Radio-protectors are described by their dose reduction factor (DRF) while radio-sensitizers are described by their enhancement ...
Foster D. Lasley +4 more
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Combined modality therapy for intracranial tumors
Cancer, 1975Three types of tumor (supratentorial astrocytoma, medulloblastoma, and craniopharyngioma), each requiring a fundamentally different therapeutic approach, will be used to illustrate the principles and practice of combined treatment in this field. The role of radiotherapy and ways of enhancing the effect of irradiation will be considered.
H. J. G. Bloom, H. J. G. Bloom
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Taxanes in Combined Modality Therapy
2003The taxanes are a relatively new group of plant-derived chemotherapeutic agents that have been studied quite extensively in both preclinical studies and in clinical trials. This group of drugs, which includes paclitaxel (Taxol) and docetaxel (Taxotere), act as mitotic spindle inhibitors through their promotion of microtubule assembly and retardation of
Hak Choy, Robert MacRae
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