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Combined modality therapy for gynecologic cancer
Current Opinion in Oncology, 1995The use of combined modality therapy in the primary management of gynecologic cancer continues to be explored. Although early ovarian cancer is treated with postoperative adjuvant treatment, the data to support its value is lacking. In advanced disease, paclitaxel has emerged as the most optimal treatment after maximal cytoreduction.
I, Ackerman, G M, Thomas
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2014
Radiation therapy can be modified by increasing the effectiveness of radiation on tumors (radiosensitizers), protecting normal tissues (radioprotectors), increasing oxygen concentration, or by using systemic therapy drugs. Radio-protectors are described by their dose reduction factor (DRF) while radio-sensitizers are described by their enhancement ...
David S. Chang +4 more
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Radiation therapy can be modified by increasing the effectiveness of radiation on tumors (radiosensitizers), protecting normal tissues (radioprotectors), increasing oxygen concentration, or by using systemic therapy drugs. Radio-protectors are described by their dose reduction factor (DRF) while radio-sensitizers are described by their enhancement ...
David S. Chang +4 more
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Combined modality therapy for pancreatic cancer
Seminars in Oncology, 2003In spite of the high mortality in pancreatic cancer, significant progress is being made. This review discusses multimodality therapy for patients with pancreatic cancer. According to several phase II trials and Gastrointestinal Tumor Study Group results, improvements in locoregional control and survival may be achieved when chemotherapy is added to ...
James Y, Tsai +2 more
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Combined‐modality therapy for gastric cancer
Seminars in Surgical Oncology, 2003AbstractGastric cancer has a poor prognosis. It is often diagnosed at an advanced stage, and potentially curative treatments often can not be exercised. Even when a curative surgical resection is possible, only a minority of patients survive beyond 5 years, and locoregional failures are frequent among patients undergoing curative resections.
James C, Yao +6 more
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Combined Modality Therapy for Rectal Cancer
The Cancer Journal, 2016The primary therapy for any potentially curative rectal cancer is surgery. For locally advanced tumors (i.e., T3-4 and/or node positive), the very high rate of local and distant recurrences has necessitated a standard adjuvant regimen of preoperative chemoradiation and postoperative chemotherapy.
Sagar A, Patel +2 more
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Combined modality therapy of malignant melanoma
World Journal of Surgery, 1979AbstractThe major modalities of therapy, namely, surgery, radiotherapy, chemotherapy, and immunotherapy, are each of value in selected cases of malignant melanoma. However, because none of these therapies, alone, is capable of curing or controlling some subgroups of melanoma patients, combined modality therapy needs to be used more extensively. Surgery
E M, Hersh, J U, Gutterman, C M, McBride
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Combined Modality Therapy of Esophageal Cancer
Journal of the National Comprehensive Cancer Network, 2008Esophageal cancer is a deadly disease. Only one third of patients with localized disease experience long-term survival. Over the past 20 years, investigators have evaluated neoadjuvant strategies to improve the outcomes of surgical management. Chemotherapy and radiation have been evaluated individually and in combination for preoperative management of ...
Rosalyn A, Juergens, Arlene, Forastiere
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Combined Modality Therapy for Rectal Cancer
The Cancer Journal, 2010The standard adjuvant treatment for cT3 and/or N+ rectal cancer is preoperative chemoradiation. However, there are many controversies regarding this approach. These include the role of short course radiation, whether postoperative adjuvant chemotherapy necessary for all patients and whether the type of surgery after chemoradiation should be based on ...
Minsky, Bd +2 more
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Combined modality therapy for intracranial tumors
Cancer, 1975Three types of tumor (supratentorial astrocytoma, medulloblastoma, and craniopharyngioma), each requiring a fundamentally different therapeutic approach, will be used to illustrate the principles and practice of combined treatment in this field. The role of radiotherapy and ways of enhancing the effect of irradiation will be considered.
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Preoperative combined modality therapy for pancreatic cancer
World Journal of Surgery, 1995AbstractCombined modality therapy can be administered prior to surgical resection for patients with operable pancreatic cancer. One important criteria used to select patients for this treatment sequence is the absence of arterial vascular encasement by tumor on thin‐section CT scanning; the absence of peritoneal seeding on surgical staging or ...
T A, Rich, D B, Evans
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