Results 91 to 100 of about 18,445,969 (262)
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Casablanca conference, January 1943: papers and minutes of meetings.
The minutes of the Combined Chiefs' meeting at the major conferences touch on virtually every policy and strategy issue of World War II, from initial troop deployments to counter Axis aggression, through the debates about the location and timing of the ...
Office, U.S. Secretary, Office of the Combined Chiefs of Staff
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Left Lung Model featuring Upper and Lower Lobes
This is a multi-colored left lung model where each color designates a specific segment of the upper and lower lobes.
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The critical period for weed control (CPWC) has been used to define weed-control threshold triggers in many cropping systems. Using the CPWC to develop a weed-control threshold for broadleaf weeds that emerge later in the season would be valuable to ...
Graham W. Charles, Ian N. Taylor
doaj +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Best practice : the mounted combined arms rehearsal.
The mounted combined arms rehearsal (CAR) adds value to the traditional terrain model CAR and provides the additional benefit of exercising the Mission Command systems that will be used to conduct the ...
Morton, Nick
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Right Lung Model featuring Upper, Middle and Lower Lobes
This is a multi-colored right lung model where each color designates a segment of the upper, middle, and lower lobes.
core
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Bimonthly magazine discussing topics related to aviation and model airplane engines including collecting, restoring, maintaining, and identifying engines, along with ...
The Model Museum
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Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source

