Results 91 to 100 of about 18,445,969 (262)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Casablanca conference, January 1943: papers and minutes of meetings.

open access: yes, 2002
The minutes of the Combined Chiefs' meeting at the major conferences touch on virtually every policy and strategy issue of World War II, from initial troop deployments to counter Axis aggression, through the debates about the location and timing of the ...
Office, U.S. Secretary, Office of the Combined Chiefs of Staff
core  

Left Lung Model featuring Upper and Lower Lobes

open access: yes, 2020
This is a multi-colored left lung model where each color designates a specific segment of the upper and lower lobes.

core  

Assessing the impact of later emerging broadleaf weeds on the critical period for weed control in high-yielding cotton

open access: yesWeed Technology
The critical period for weed control (CPWC) has been used to define weed-control threshold triggers in many cropping systems. Using the CPWC to develop a weed-control threshold for broadleaf weeds that emerge later in the season would be valuable to ...
Graham W. Charles, Ian N. Taylor
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Best practice : the mounted combined arms rehearsal.

open access: yes, 2017
The mounted combined arms rehearsal (CAR) adds value to the traditional terrain model CAR and provides the additional benefit of exercising the Mission Command systems that will be used to conduct the ...
Morton, Nick
core  

Right Lung Model featuring Upper, Middle and Lower Lobes

open access: yes, 2020
This is a multi-colored right lung model where each color designates a segment of the upper, middle, and lower lobes.

core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Sub-series 2: Publications

open access: yes, 1989
Bimonthly magazine discussing topics related to aviation and model airplane engines including collecting, restoring, maintaining, and identifying engines, along with ...
The Model Museum
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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