Results 231 to 240 of about 18,445,969 (262)

Clinic, CT radiomics, and deep learning combined model for the prediction of invasive pulmonary aspergillosis. [PDF]

open access: yesBMC Med Imaging
Zhang K   +9 more
europepmc   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

A deep learning-clinical combined model with SHapley Additive exPlanations (SHAP) method for assessing the tumor spread through air spaces in lung adenocarcinoma: a multicohort retrospective study. [PDF]

open access: yesQuant Imaging Med Surg
Zhang R   +16 more
europepmc   +1 more source

Predicting joint space changes in knee osteoarthritis over 6 years: a combined model of TransUNet and XGBoost. [PDF]

open access: yesQuant Imaging Med Surg
Guo J   +9 more
europepmc   +1 more source

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