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Combined Oral Contraceptives As Victims of Drug Interactions. [PDF]

open access: yesDrug Metab Dispos, 2023
Combined oral contraceptives (COCs) are widely used in women of reproductive age in the United States. Metabolism plays an important role in the elimination of estrogens and progestins contained in COCs. It is unavoidable that a woman using COCs may need
Li L, Yang X, Tran D, Seo SK, Lu Y.
europepmc   +2 more sources

Review of the literature on combined oral contraceptives and cancer. [PDF]

open access: yesEcancermedicalscience, 2022
Millions of women have given preference to the use of combined oral contraceptives (COCs) since its introduction in the 1960s. Both oestrogens and progestogens can regulate proliferation and it is plausible these effects may contribute to carcinogenesis.
Kamani M, Akgor U, Gültekin M.
europepmc   +2 more sources

Combined Oral Contraceptives and Venous Thromboembolism: Review and Perspective to Mitigate the Risk. [PDF]

open access: yesFront Endocrinol (Lausanne), 2021
Many factors must be considered and discussed with women when initiating a contraceptive method and the risk of venous thromboembolism (VTE) is one of them.
Morimont L   +4 more
europepmc   +2 more sources

Combined oral contraceptives containing estradiol valerate vs ethinylestradiol on coagulation: A randomized clinical trial. [PDF]

open access: yesActa Obstet Gynecol Scand, 2022
Contraceptives containing ethinylestradiol (EE) induce changes in the coagulation system and are associated with a risk of venous thromboembolism. However, studies comparing the effects of combined oral contraceptives containing EE and low‐potency ...
Haverinen AH   +9 more
europepmc   +2 more sources

Over-the-counter access to combined oral contraceptives for individuals with hypertension: an expert review [PDF]

open access: yesAmerican Journal of Preventive Cardiology
Efforts are underway to move a combined oral contraceptive over the counter in the United States. However, hypertension is an important contraindication and questions exist regarding how users should screen for it in an over-the-counter setting.
Kate Grindlay   +6 more
doaj   +2 more sources

Estimate of venous thromboembolism and related-deaths attributable to the use of combined oral contraceptives in France. [PDF]

open access: yesPLoS ONE, 2014
PURPOSE: To estimate the number of venous thromboembolic events and related-premature mortality (including immediate in-hospital lethality) attributable to the use of combined oral contraceptives in women aged 15 to 49 years-old between 2000 and 2011 in ...
Aurore Tricotel   +3 more
doaj   +2 more sources

Oral contraceptives combined with interferon β in multiple sclerosis [PDF]

open access: yesNeurology: Neuroimmunology & Neuroinflammation, 2015
Objective: To test the effect of oral contraceptives (OCs) in combination with interferon β (IFN-β) on disease activity in patients with relapsing-remitting multiple sclerosis (RRMS).
C. Pozzilli   +10 more
semanticscholar   +5 more sources

Use of combined oral contraceptives and risk of venous thromboembolism: nested case-control studies using the QResearch and CPRD databases [PDF]

open access: yesBritish medical journal, 2015
Objective To investigate the association between use of combined oral contraceptives and risk of venous thromboembolism, taking the type of progestogen into account. Design Two nested case-control studies.
Y. Vinogradova   +2 more
semanticscholar   +5 more sources

Thrombin generation in a woman with heterozygous factor V Leiden and combined oral contraceptives: A case report [PDF]

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2020
Combined oral contraceptives and factor V Leiden mutation are multiplicative risk factors for venous thromboembolism. However, it remains unknown whether this multiplicative effect is reflected in thrombin generation assays.
Maxime G. Zermatten   +3 more
doaj   +2 more sources

Oxidative Stress in Female Athletes Using Combined Oral Contraceptives [PDF]

open access: yesSports Medicine - Open, 2016
BackgroundOxidative stress in female athletes is understudied. We investigated oxidative stress in sportswomen of different disciplines according to combined oral contraceptive (OC) use and lifestyle/alimentary habits.MethodsItalian sportswomen (n = 144;
S. Cauci   +3 more
semanticscholar   +3 more sources

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