Results 81 to 90 of about 2,170,131 (275)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

A Sparse Multi-Scale Algorithm for Dense Optimal Transport

open access: yes, 2016
Discrete optimal transport solvers do not scale well on dense large problems since they do not explicitly exploit the geometric structure of the cost function.
Schmitzer, Bernhard
core   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

JUSTIFICATION OF INTEGRATED CRITERION OF COMBINED TRANSPORT COMPANY EFFICIENCY [PDF]

open access: yesAvtomobilʹnyj Transport (Harʹkov), 2013
The method of grounding of performance criteria of combined transport company with respect to the municipality, the passenger and the carrier is offered.
Mospan, V.
doaj  

Možnosti in pogoji vključevanja JŽ v mednarodni kopenski kontejnerski transport

open access: yesPromet (Zagreb), 2012
This paper deals with the development aspected orientation of the combined transport in Europe, in the first place of the EC member states, Austria and Switzerland, for the author to subsequently review the traffic policy and measures for the advancement
Tatjana Kobilica
doaj   +1 more source

E-business impacts for urban freight: results from an Australian study [PDF]

open access: yes, 2002
E-Business is expected to dramatically change the way business is conducted internationally, nationally, within states and at the local area level.
Ferreira, Luis   +2 more
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Millimetre-long transport of photogenerated carriers in topological insulators. [PDF]

open access: yes, 2019
Excitons are spin integer particles that are predicted to condense into a coherent quantum state at sufficiently low temperature. Here by using photocurrent imaging we report experimental evidence of formation and efficient transport of non-equilibrium ...
Clark Travaglini, Henry   +13 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

COMBINED TRANSPORT OF CONTAINERS ON THE LOWER VISTULA

open access: yesContemporary Economy, 2017
One of the methods of achieving sustainable transport development and implementing the climate policy is to increase the importance of inland waterway transport in combined transport.
Ryszard Rolbiecki
doaj  

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