Results 111 to 120 of about 81,496 (301)
Vulnerable workers in insecure jobs: A critical meta‐synthesis of qualitative findings
Abstract Job insecurity is a widespread workplace stressor that has been extensively investigated using quantitative approaches. With the use of a critical organisational psychology framework, we conducted a meta‐synthesis of 20 qualitative studies to investigate the experience of job insecurity among vulnerable employee groups (i.e., women and ...
Andrea Bazzoli, Tahira M. Probst
wiley +1 more source
Three Interesting 15th and 16th Century Comet Sightings in Kashmiri Chronicles [PDF]
This note is about three interesting 15th and 16th century sightings of comets in Kashmiri chronicles. We provide reasons for their identification as the 1468 S1, 1531 (Halley's), and 1533 M1 comets.
arxiv
Abstract Gene expression biomarkers have the potential to identify genotoxic and non‐genotoxic carcinogens, providing opportunities for integrated testing and reducing animal use. In August 2022, an International Workshops on Genotoxicity Testing (IWGT) workshop was held to critically review current methods to identify genotoxicants using ...
Roland Froetschl+14 more
wiley +1 more source
Ribonucleoprotein transport in Negative Strand RNA viruses
The genome replication of Negative‐sense, single‐stranded RNA viruses most‐often segregate in membrane‐less environments called inclusion bodies (IBs). These “organelles” usually locate far from the cell surface from where new virions are released. Here, for each viral family, we discuss how the genome progeny is transported from the IBs to reach the ...
Cédric Diot+2 more
wiley +1 more source
55P is a periodic comet with an orbital period of 33 years. It fits the classical definition of a Halley-type comet. The comet is the parent body of the Leonid meteor shower. Orbital simulation of the comet’s 55P/Tempel-Tuttle orbit for 5000 years before
R. A. Guliyev
doaj +1 more source
Terrestrial Reproduction of the Spectra of the Tails of Recent Comets : (Plate 8.) [PDF]
Allan Fowler
openalex +1 more source
Review of Transcriptomic Biomarkers That Predict In Vitro Genotoxicity in Human Cell Lines
ABSTRACT The current genotoxicity testing paradigm provides little mechanistic information, has poor specificity in predicting carcinogenicity in humans, and is not suited to assessing a large number of chemicals. Genomic technologies enable the characterization of genome‐wide transcriptional changes in response to chemical treatments that can inform ...
Heng‐Hong Li+7 more
wiley +1 more source
Benchmark Response (BMR) Values for In Vivo Mutagenicity Endpoints
ABSTRACT The benchmark dose (BMD) approach constitutes the most effective and pragmatic strategy for the derivation of a point of departure (PoD) for comparative potency analysis, risk assessment, and regulatory decision‐making. There is considerable controversy regarding the most appropriate benchmark response (BMR) for genotoxicity endpoints.
Paul A. White+8 more
wiley +1 more source
SETDB1 regulates microtubule dynamics
SETDB1 association with microtubules inhibits microtubule polymerization and enhances their instability. SETDB1 may affect the microtubules by interacting with HDAC6 to enhance HDAC6 tubulin deacetylation activity. Abstract Objectives SETDB1 is a methyltransferase responsible for the methylation of histone H3‐lysine‐9, which is mainly related to ...
Rosari Hernandez‐Vicens+4 more
wiley +1 more source