N- to C-Glycoside Rearrangement of Uridine 5'-Phosphate in Two Enzymatic Steps for the Production of Pseudouridine 5'-Phosphate. [PDF]
The authors present a streamlined cascade reaction for one‐pot N‐C rearrangement of uridine‐5′‐phosphate (UMP) to pseudouridine‐5′‐phosphate (ΨMP; a key mRNA vaccine building block), in two enzymatic steps catalyzed by UMP nucleosidase (EC 3.2.2.10) and ΨMP C‐glycosidase (EC 4.2.1.70).
Pfeiffer M, Guld F, Nidetzky B.
europepmc +2 more sources
Abstract JAXA's Hayabusa2 sample return mission visited the volatile‐rich carbonaceous (C‐type) asteroid (162173) Ryugu with the aim of ground‐truthing remote observations, returning a pristine sample from a C‐type asteroid, and strengthening links between asteroids and the meteorite collection. Here, we have conducted a systematic study of coarse (>10
C. S. Harrison+26 more
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Management of Intraocular Pressure Elevation After Commercially Available Cultivated Oral Mucosal Epithelial Cell Transplantation for Limbal Stem Cell Deficiency. [PDF]
Goto H+6 more
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Vitrectomy as a rapid diagnostic tool for lymphoma: Cytology and flow cytometry approach
British Journal of Haematology, EarlyView.
Pierre Gascon+16 more
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Abstract Refractory inclusions (RIs) in chondrites are widely used as tracers of early solar system formation conditions. In the context of sample‐return missions, a non‐destructive and non‐invasive analytical tool that can rapidly detect and characterize RIs in space samples during their early phase of study is highly needed.
Jean Charlier+4 more
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Re-assessment of the risks to public health related to the genotoxicity of styrene present in plastic food contact materials. [PDF]
EFSA Panel on Food Contact Materials (FCM)+18 more
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Journée d’étude « La maison médiévale »
Anaïs Comet
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In Vitro Study of the Effects of Pesticide Mixtures Used in Maize Cultivation in Ecuador. [PDF]
Arévalo-Jaramillo AP+3 more
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ABSTRACT Humulus lupulus L., commonly known as hop, is a perennial crop grown worldwide and is well known for its pharmacological, commercial, and most importantly brewing applications. For hundreds of years, hop has undergone intense artificial selection, with over 250 cultivated varieties being developed worldwide, all displaying differences in key ...
Alexandra McElwee‐Adame+17 more
wiley +1 more source
Evaluation of the Genotoxicity and Cytotoxicity of Bioceramic Endodontic Sealers in HepG2 and V79 Cell Lines: An In Vitro Study Using the Comet and Micronucleus Assays. [PDF]
Tadin A+6 more
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