Results 191 to 200 of about 120,456 (335)

A Self‐Organized Liquid Reaction Container for Cellular Memory

Advanced Science, EarlyView.
How cells restore epigenetic information lost during replication is not known. This work proposes a mechanism based on the formation of biomolecular condensates. These condensates are induced by the chromosome itself and serve as reaction vessels for reconstructing missing epigenetic markers.
Sukanta Mukherjee, Enrico Skoruppa, Holger Merlitz, Jens‐Uwe Sommer, Helmut Schiessel   +4 more
wiley   +1 more source

Improving measurement of girls and young women's reproductive experiences: qualitative findings from research in Kenyan family planning clinics. [PDF]

BMJ Public Health
Hartman EA, Colombini M, Namwebya J, Asala E, Ombidi W, Thungu F, Singh NS, Buller AM, Marston C.   +8 more
europepmc   +1 more source

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

Advanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen, Yuxiong Guo, Qing Zhao, Jingping Liu, Shuyi Kuang, Zhengcong Huang, Chenlin Lv, Shuxiu Xu, Zekai Zhuang, Anyan Yang, Jing Li, Kai Wu, Yumei He   +12 more
wiley   +1 more source

[Commemoration of the Special Issue on Tuberculosis in "<i>Public Health Weekly Report</i>"]. [PDF]

Jugan Geongang Gwa Jilbyeong
Choi BY.
europepmc   +1 more source

Kindled emotions: Commemoration and the importance of meaning making, support and recognition. [PDF]

PLoS One, 2023
Mitima-Verloop HB, Mooren TTM, Boelen PA.   +2 more
europepmc   +1 more source

GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer

Advanced Science, EarlyView.
Aberrant glycosylation drives cancer progression, yet its role in the tumor microenvironment remains unclear. We developed GlycoChat to map glycan–lectin circuits at single‐cell resolution. We discovered that cancer cells induce immunosuppressive macrophage differentiation and impair phagocytosis through interactions with CLEC10A and SIGLEC3 ...
Dinh Xuan Tuan Anh, Sunanda Keisham, Arun Burramsetty, Lalhaba Oinam, Koichiro Kumano, Akihiro Kuno, Osamu Shimomura, Tatsuya Oda, Hiroaki Tateno   +8 more
wiley   +1 more source

Lifetime risk, sex and age differences in annual incidence of ocular motor cranial nerve palsy in Japan for 2019. [PDF]

Commun Med (Lond)
Miyata M, Kido A, Miyake M, Tamura H, Kamei T, Wada S, Ueshima H, Nakao S, Yamamoto A, Suda K, Nakano E, Tagawa M, Mori Y, Tsujikawa A.   +13 more
europepmc   +1 more source

Soft‐Drug‐Inspired MnSTF Nano‐Adjuvant for Safe and Synergistic cGAS–STING Activation in Tumor Immunotherapy

Advanced Science, EarlyView.
This study introduces MnSTF, a soft‐drug‐inspired nanoadjuvant that overcomes the systemic toxicity of STING agonists. Through Mn2+ coordination with an ENPP1 inhibitor, it enables safe cGAS‐STING activation, remodels the tumor immune microenvironment, and synergizes with radiotherapy or vaccines to elicit robust antitumor immunity.
Guangfei Sun, Jiancheng Pan, Rui Li, Ruoxi Li, Ziyan Liu, Jinhui Wu, Tingsheng Lin, Yiqiao Hu, Ahu Yuan   +8 more
wiley   +1 more source

Functional Difference of MYC and MYCN in Combined Hepatocellular-Cholangiocarcinoma: Regulation of Differentiation by HNF1B. [PDF]

Cancer Sci
Goto M, Yamamoto M, Tanaka H, Fujii Y, Takasawa K, Kamikokura Y, Kamikokura M, Kobayashi N, Murakami T, Nishikawa Y, Takasawa A.   +10 more
europepmc   +1 more source

Synthesis and Gas Permeability of Copoly (trimethylsilylpropyne-phenylpropyne) Membranes (Commemoration Issue Dedicated to Professor Hisashi Odani On the Occasion of His Retirement)

, 1992
Tsutomu Nakagawa, Kazukiyo Nagai, Akon Higuchi   +2 more
openalex   +1 more source