Results 131 to 140 of about 3,521,810 (225)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Validating self-reported exclusive breastfeeding in Eswatini using stable isotope techniques. [PDF]

open access: yesPLoS One
Simelane KS   +7 more
europepmc   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Response to article by Ruochen Bao et al., “Bibliometric analysis of immunotherapy for bladder cancer: A correspondence”

open access: yesHuman Vaccines & Immunotherapeutics
Ziqi Zhao   +4 more
doaj   +1 more source

Commentary: Acetaminophen Enhances the Reflective Learning Process

open access: yesFrontiers in Psychology, 2019
Jonathon McPhetres
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Comment on “Intravenous Lidocaine Compared with Quadratus Lumborum Block on Postoperative Analgesia Following Laparoscopic Renal Surgery: Protocol for a Randomized Noninferiority Trial” [Letter]

open access: yesJournal of Pain Research
Xuefan Zeng,1,* Yiwei Wang2,* 1Chongqing Medical University, Chongqing, People’s Republic of China; 2Tianjin University of Traditional Chinese Medical, Tianjin, People’s Republic of China*These authors contributed equally to this ...
Zeng X, Wang Y
doaj  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Hepatitis C distribution across diverse population groups in the Eastern Mediterranean Region: An umbrella review. [PDF]

open access: yesPLoS One
Abdolahinia Z   +5 more
europepmc   +1 more source

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