Results 51 to 60 of about 1,537,789 (342)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Customs union: Old instrument, new function in EU-Turkey relations [PDF]

open access: yes, 2020
The European Council’s conclusions on external relations published on 1 October 2020 hint at the readiness of the European Union (EU) to enter into a new stage in its relations with Turkey.
Wasilewski, Karol   +7 more
core   +1 more source

UN-General Assembly of "hope": a more collaborative debate, an innovative report, and an SDG moment [PDF]

open access: yes, 2021
Even though the 76th United Nations General Debate had to take place in a hybrid format yet again due to the pandemic, the overall mood was more positive than last year.
Beisheim, Marianne
core   +1 more source

Supporting Survivor‐Centered Care Through Digital Health Integration

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Survivors of childhood cancer face barriers to receiving guideline‐based, long‐term follow‐up care. Two digital tools, Passport for Care (PFC) and Cancer SurvivorLink (SurvivorLink), address complementary gaps by enabling tailored survivorship care plan (SCP) generation, updating, storage, and sharing.
Jordan G. Marchak   +15 more
wiley   +1 more source

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi   +6 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Tefsir Metodolojisinde Anlam-Yorum Ayrımının Temelleri

open access: yesCumhuriyet İlahiyat Dergisi, 2018
Kur’ân’ı re’y ile tefsir etmekten sakındıran hadisler ve haberler varken hakkında rivayet olmayan âyetlerin nasıl anlaşılacağı meselesi tefsir ilminin mahiyeti ile ilgilidir.
Muhammed Yüksek
doaj   +1 more source

Covid-19 in the Horn of Africa: gaining trust in a crisis [PDF]

open access: yes, 2020
On reaching the Horn of Africa, the corona virus will have encountered countries already facing a multitude of challenges. Prolonged armed conflict, drought and insecurity have turned more than eight million people into refugees in their own countries ...
Weber, Annette
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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