Results 61 to 70 of about 3,524 (226)

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

Advanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian, Qianyu Wang, Wenyan Gao, Xianfeng Li, Jiawen Fan, Xiaoliang Wu, Siqi Liu, Xiangdong Ming, Danna Yeerken, Mutian Shen, Qingjie Min, Qimin Zhan, Yan Wang   +12 more
wiley   +1 more source

Glucose and Glutamine Deprivation Promotes Breast Cancer Lung Metastasis via BRD4‐Dependent Enhancer Activation

Advanced Science, EarlyView.
To model a nutrient‐restricted tumor microenvironment, breast cancer cells were adapted to low glucose and glutamine levels. In the adapted cells, BRD4‐driven enhancer activation increases pro‐invasive EDN1 expression, facilitated by ATF3/c‐JUN and reinforced by enhancer RNA.
Poshan Yugal Bhattarai, Arathy Vasukutty, Yujin Na, Sung‐Chul Lim, Hong Seok Choi   +4 more
wiley   +1 more source

A Preclinical Multifunctional Capsule Robot with Unified Diagnosis and Targeted Thermal Therapy for Gastrointestinal Diseases

Advanced Science, EarlyView.
A proof‐of‐concept multifunctional capsule robot integrates diagnostic imaging, magnetic navigation, wireless power transfer, and targeted thermotherapy for gastrointestinal applications. Magnetically guided positioning and stable wireless power enable localized thermal ablation, achieving controlled heating and high cell mortality in vitro.
Heng Zhang, Yichong Sun, Xiaoting Zhang, Chi‐Kwan Lee, Zheng Li, Yehui Li, Huarong Chen, Paul D. Mitcheson   +7 more
wiley   +1 more source

A cointegrating stock trading strategy: application to listed tanker shipping companies

Journal of Shipping and Trade, 2019
In the current paper, we propose a strategy to trade a portfolio of listed shipping companies in the US market. In particular, we estimate a co-integrating relationship between the weekly stock market returns of a portfolio of tanker shipping companies ...
Nektarios A. Michail, Konstantinos D. Melas   +1 more
doaj   +1 more source

Synthetic Shewanella‐Bacillus Microbial Consortia for Enhanced Metal Oxide Leaching From Spent Lithium‐Ion Batteries Using Brewing Wastewater as Leaching Agent

Advanced Science, EarlyView.
A recycling approach of spent lithium‐ion batteries is developed using brewing wastewater as the leaching agent and an engineering microbial consortium as the biocatalyst. Shewanella oneidensis reduces spent LiNixCoyMn1‐x‐yO2 cathodes via extracellular electron transfer, while Bacillus subtilis removes residual ethanol to eliminate inhibition.
Baocai Zhang, Chunxiao Qiao, Huichun Liu, Yiyun Wang, Yan Liu, Huan Yu, Junqi Zhang, Chao Li, Deguang Wu, Qulai Tang, Zhiwen Wang, Danni Zhang, Dake Xu, Feng Li, Hao Song   +14 more
wiley   +1 more source

Supply chain risk management processes for resilience: A study of South African grocery manufacturers

Journal of Transport and Supply Chain Management, 2017
Background: The supply chain risk management (SCRM) process is aimed at the implementation of strategies that assist in managing both daily and exceptional risks facing the supply chain through continuous risk assessment to reduce vulnerability and ...
Simon Simba, Wesley Niemann, Theuns Kotzé, Assilah Agigi   +3 more
doaj   +1 more source

Déplacements et commerces : impacts d'un transport en commun en site propre de surface sur le commerce. Le cas de l'agglomération strasbourgeoise

, 2003
L’étude a été réalisée par l’agence de développement et d’urbanisme de l’agglomération strasbourgeoise pour le CERTU dans le cadre du Programme « Interface Urbanisme-Déplacements », commandé par le Ministère de l’Equipement, afin d‘alimenter le thème 4 de ce programme « Impacts des mesures des plans de déplacements urbains sur les activités économiques
Vimbert, Benoît, Scaravella, Julien, Vigneron, Fabienne, Koenig, Colette, Mille, Marie-Noëlle   +4 more
openaire   +1 more source

Multi‐Tissue Crosstalk Regulating Meniscus Healing Under Inflammation and Physiological Loading

Advanced Science, EarlyView.
Using a novel Meniscus‐on‐a‐chip (MoC) model integrated with a meniscus‐specific bioreactor, this study investigated the roles of multi‐tissue crosstalk that regulates injury, healing, and degeneration of the meniscus injury under inflammation and pathophysiological loading.
Hun Jin Jeong, Elen Zhu, Min Seo Kang, Ming Wang, Sam Comito, Chang H. Lee   +5 more
wiley   +1 more source

Ionic Liquid Electrolytes for Extreme Temperature Conditions: Challenges and Perspective

Angewandte Chemie, EarlyView.
Ionic liquids (ILs) have gained great attention as safe electrolyte components in recent years. This review elucidates the temperature effects on IL‐based electrolytes from molecular configurations, physicochemical properties, and interfacial chemistry, raises the challenges and design strategies operating at low‐ and HT, providing valuable guidance ...
En Xie, Chengdong Liu, Xinghao Wang, Jian Wang, Zhen Chen, Huihua Li, Wenlong Cai, Hao Li, Yang Peng, Fanglin Wu, Stefano Passerini, Haolin Tang   +11 more
wiley   +2 more sources

The “Belt and Road Initiative”: impacts on TEN-T and on the European transport system

Journal of Shipping and Trade, 2019
China’s Belt and Road Initiative, announced in late 2013, includes the construction of land-based transport connections between Asia and Europe, the creation of an economic belt for Eurasian cooperation, and maritime routes between China and all ...
Dick Dunmore, Alberto Preti, Clémence Routaboul   +2 more
doaj   +1 more source