Results 91 to 100 of about 2,093,228 (306)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

LA NOCHE BUENA EN LA ALAMEDA: DESCRIPCIÓN DE UNA TRADICIÓN EN TIEMPOS DE MODERNIZACIÓN. SANTIAGO DE CHILE, SEGUNDA MITAD DEL SIGLO XIX

open access: yesHistoria (Santiago), 2012
La celebración de la Navidad en la Alameda fue uno de los momentos más importantes del año en el Santiago de la segunda mitad del siglo XIX. A partir de lo visto en la prensa de la capital de ese período, junto a otras fuentes escritas y visuales, en ...
ELISA SILVA GUZMÁN
doaj  

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Commerce

open access: yesScientific American
Poursuite de l’invasion de l’Ukraine, guerre dans la bande de Gaza, crise alimentaire, transition énergétique sans précédent, rééquilibrage géostratégique, montée du populisme, ingérence de toute sorte, explosion du recours à l’intelligence artificielle, inflation à maîtriser, voilà autant de traits caractérisant l’année 2023 et ayant eu le potentiel ...
Geneviève Dufour   +2 more
  +4 more sources

Les réglementations en matière de l’inexécution du contrat dans le contexte du rapprochement du droit privé européen

open access: yesEIRP Proceedings, 2009
With a view to European integration, harmonisation of the Moldovan legislation to Europeanstandards has become an imperative. An important area of harmonisation is the contract law. The ViennaConvention on the International Sale of Goods of 11 April 1980
Aurel Baiesu
doaj  

Integrating customer relationship management strategies in (B2C) e-commerce environments

open access: yes, 2003
Creating value and generating a total customer experience(TCE ) is important for E -Commerce in order to attract customers. However, with increasing competition in the marketplace, it is becoming increasingly difficult to retain customers.
Dawson, Liisa   +2 more
core  

The Road Ahead for the U.S. Auto Industry [PDF]

open access: yes, 2005
[Excerpt] In 2004, U.S. light vehicle sales were up slightly, reversing a moderate slide that began in 2001. The 1.3 percent gain brought the market total to 16.8 million units, approximately the same level as 2002, and the fourth highest sales on record.
International Trade Administration, U.S. Department of Commerce
core   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin   +11 more
wiley   +1 more source

Le commerce entre l’Italie et l’Orient entre xe et xiiie siècle : nouvelles polarités et reconfiguration des réseaux d’échanges

open access: yesCahiers d’Études Italiennes, 2017
It is usually admitted that the expansion of Italian merchants in Orient is the sole result of the political and economic power of Northern Italian cities and of the development of pre-capitalism in Europe.
Dominique Valérian
doaj   +1 more source

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