Results 41 to 50 of about 7,830,564 (299)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Riley v. Northern Commercial: Commercial Rationale Triumphs Over Statutory Interpretation [PDF]
, 1984 Earlier studies point at that the notion of working in a project brings with it expectations on several aspects of the work situation, expectations that are institutionally given by project theory and practice and re-constructed by the project workers in
Lindgren, Monica, Packendorff, Johann
core +1 more source
Scheduling commercial advertisements for television [PDF]
, 2014 The problem of scheduling the commercial advertisements in the television industry is investigated. Each advertiser client demands that the multiple airings of the same brand advertisement should be as spaced as possible over a given time period ...
Garcia-Villoria, Alberto, Salhi, Said
core +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Commercial Applications Multispectral Sensor System [PDF]
, 1993 NASA's Office of Commercial Programs is funding a multispectral sensor system to be used in the development of remote sensing applications. The Airborne Terrestrial Applications Sensor (ATLAS) is designed to provide versatility in acquiring spectral and ...
Birk, Ronald J., Spiering, Bruce
core +1 more source
Determinants of Commercial Banks’ Lending Behavior in Nigeria [PDF]
, 2011 This study investigated the determinants of commercial banks’ lending behaviour in the Nigerian context. The study aimed to test and confirm the effectiveness of the common determinants of commercial banks lending behaviour and how it affects the ...
Olokoyo, F. O.
core +1 more source
Banking system of the USA, Germany and Japan: comparative analysis
Ученые записки Российской академии предпринимательства, 2021 In article the comparative analysis of formation and development of a banking system of the USA, Germany, Japan is carried out, are revealed strong and weaknesses of each of bank systems, measures for their further development and improvement are offered.
A. I. Vinogradov
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