Results 51 to 60 of about 7,830,564 (299)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Introduction: Commercial Diplomacy and International Business. [PDF]
, 2012 International business has always been intimately linked to the politics of the global economy. Expansion and investment strategies of business play a key role in de?ning the architecture of the global economy.
Lee, D., Ruel, H.J.M.
core +4 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Shacklefords Commercial Development Analysis [PDF]
, 2019 King and Queen County believes that economic development is crucial to ensuring a stable economy and high quality of life for residents of the county. With an out-commuting rate of 71% for the entire Middle Peninsula region, residents and businesses are ...
Krane, Vegas +6 more
core +1 more source
Economic Governance to Expand Commercial Wetlands: Within- and Cross-Scale Challenges [PDF]
, 2011 Commercial wetlands are defined as wetlands directed by an entrepreneur with the intention of making a profit. The combination of ecosystem services that commercial wetlands can provide seems to be an attractive societal perspective.
Blaeij, A.T., de +2 more
core +3 more sources
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
It Depends on What the Meaning of False is: Falsity and Misleadingness in Commercial Speech Doctrine [PDF]
, 2007 While scholarship regarding the Supreme Court\u27s noncommercial speech doctrine has often focused on the level of protection for truthful, non-misleading commercial speech, scholars have paid little attention to the exclusion of false or misleading ...
Tushnet, Rebecca
core +2 more sources
More than putting on a performance in commercial homes: merging family practices and critical hospitality studies [PDF]
, 2015 Critical hospitality studies and family studies have shown a developing theoretical convergence predicated by the ‘social turn’ in the study of hospitality.
Seymour, Julie
core +1 more source
Journal of Veterinary Internal Medicine, 2020 Background High dietary phosphorus (P) and low calcium‐to‐phosphorus ratio (Ca:P) are associated with kidney damage in cats. There are no established guidelines for dietary P maximum for cats.
Stacie C. Summers +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source