Results 71 to 80 of about 1,302,047 (307)

ETV4 Promotes Colorectal Cancer Progression by Reprogramming Asparagine Metabolism to Remodel the Stromal Microenvironment

Advanced Science, EarlyView.
ETV4 coordinates a dual transcriptional program by upregulating MET and asparagine synthetase (ASNS). The resulting asparagine (Asn) secretion acts as a metabolic signal, reprogramming hepatic stellate cells (HSCs) and primary cancer‐associated fibroblasts (CAFs) toward an inflammatory phenotype. These activated stromal cells release HGF to sustain the
Dujiang Fu, Meijia Zhang, Maoping Cai, Miao Wang, Ziao Huang, Zesheng Lin, Yixin Liu, Wang Qian, Guopeng Chen, Yuxing Liang, Dongyi Wei, Jing xie, Picheng Yan, Yuanyuan Qu, Yongchang Wei   +14 more
wiley   +1 more source

Innovative resource synergy, market integration, and new quality productive forces: testing based on threshold and moderating effects

Future Business Journal
To foster the development of new quality productive forces (NPF), it is imperative to advance market integration (MI) and optimize the synergy of innovation resources (IRS).
Shujuan Wu, Daqian Huang, Jinting Li, Jianhua Xiao   +3 more
doaj   +1 more source

Does the implementation of economic policies connected to climate change depend on monetary policy mandates and financial stability governance structures?

Heliyon
The objective of the proposed research study is to examine how the economic policy mandates and governance frameworks of central banks affect the implementation of climate-related economic measures.
Liu Cheng, Chang Wu
doaj   +1 more source

Cryo‐EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits

Advanced Science, EarlyView.
The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang, Zhaxi Zerang, Linjin You, Ziye Liu, Rong Nie, Fuwei Qi, Fenfen Gao, Chengmu Zhao, Wantong Ma, Jinghan He, Xiaoru Wang, Shanquan Wu, Bo Liu, Xinyao Liu, Dongsheng Lei, Dejuan Zhi, Dongsheng Wang   +16 more
wiley   +1 more source

Deregulation of Bank Entry and Branching: Impact on Competition [PDF]

Does deregulation of entry and branching restrictions in the country's commercial banking sector foster a more competitive atmosphere? What are the effects of the regulatory restrictions on bank entry and branching on the structure, conduct and ...
Milo, Melanie S.
core  

Effects of automated teller machine service quality on customer satisfaction: Evidence from commercial bank of Ethiopia. [PDF]

Heliyon, 2023
Nigatu AG, Belete AA, Habtie GM.
europepmc   +1 more source

Myeloid‐Derived Grancalcin Promotes Periodontal Inflammation and Pathological Bone Remodeling in Periodontitis

Advanced Science, EarlyView.
Grancalcin (GCA), a myeloid‐derived protein, is enriched in gingival tissues of periodontitis patients and mouse models. Through interactions with CD44 and activation of MYH9, GCA promotes NF‐κB signaling and exacerbates periodontal inflammation and bone loss.
Min Zhou, Yao Xiao, Ziyue Xu, Chengyu Yang, Jiang Li, Ya Liu, Ping Yin   +6 more
wiley   +1 more source

Assessing the economic impact of climate risk on green and low-carbon transformation

Frontiers in Environmental Science
IntroductionLimate risk poses significant challenges to sustainable development, particularly in the context of transitioning to green and low-carbon economies. The complexity of these interactions makes it difficult to devise strategies that effectively
Chen Qin, Hongli Lou, Li Li
doaj   +1 more source

Peć's Commercial-industrial Bank [PDF]

Baština, 2014
In order to protect Serbian civic class from the decline, in Peć 1907 was founded the Fund of 'The Holy Mother of God of Miraculous Icon Pećska'. By liberation from the Osman's authority and becoming the part of the Kingdom of Montenegro, which fully ...
Becić Ivan M.
doaj  

The influence of banking liquidity risk on profitability: The moderating role of capital adequacy ratio [PDF]

Banks and Bank Systems
The decline in bank liquidity due to slowing economic growth in Indonesia has decreased bank profitability. COVID-19 and the increase in the number of non-performing loans increased the level of bank liquidity risk and decreased capital.
Meliza, Norraidah Abu Hasan, Hermilasari Saputri   +2 more
doaj   +1 more source