Results 31 to 40 of about 56,045 (311)
Molecular Oncology, EarlyView.Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka +10 more
wiley +1 more source
CEO power and bank risk in the UAE [PDF]
Banks and Bank Systems, 2020 The lessons from the 2008 global financial crisis show that excessive risk taking and governance failures contribute to the failure of several banks.
Haileslasie Tadele, Baliira Kalyebara
doaj +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Banks’ Leverage Evolution: The Case of Commercial Banks
Mathematics, 2023 This paper used a panel dataset on the post-Basel-I period to compare the evolution of leverage ratios between commercial and investment banks before the 2007 financial crisis.
Michele Piffer
doaj +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Disclosure of Corporate Social Responsibility Practices
Journal of Accounting and Finance in Emerging Economies, 2020 This study aimed to depict the disclosure of corporate social responsibility (CSR) practices of commercial banks in Bangladesh. The sample included annual reports for the year 2018 of twenty-eight commercial banks out of thirty commercial banks listed on
Md Morshadul Hasan
doaj +1 more source
A Study of Subsidy Policy in the Ship Financing Market [PDF]
Journal of International Logistics and Trade, 2017 This study considers the case in which governments decide whether to support private commercial banks with a subsidy policy in order to encourage participation in the international ship financing market.
Min-Hwan Lee, Ho-Cheol Nam
doaj +1 more source
Factors affecting supply chain efficiency in commercial banks’ operations – Case in Vietnam
Cogent Business & Management, 2023 The paper aims to estimate factors affecting supply chain efficiency in commercial banks’ operations in Vietnam. To achieve this objective, the study uses structural equation modeling (SEM) to define the determinants of supply chain efficiency in ...
Kim Quoc Trung Nguyen, Hang Minh Nguyen
doaj +1 more source
Advanced Biology, EarlyView.HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang +6 more
wiley +1 more source