Results 31 to 40 of about 1,364,834 (359)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Compact device for mass transfer between liquid films and vapour or gas [PDF]
, 2008 University Carlos III of Madrid (Spain) offers a method and device for mass transfer between liquid and vapour or gas. Applications to absorbers and desorbers in absorption chiller technology, evaporators, condensers and chemical reactors.
Acosta Iborra, Antonio
core +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Commercial company winding-up through liquidation [PDF]
Civitas, 2018 The paper examines one of the ways of winding up a company in absolute terms, through liquidation. This is a procedure conducted over a solvent company, settling all creditors' claims regardless of whether the procedure has been initiated and managed by the company shareholders themselves or by the Companies House.
Miroslav Milosavljević +1 more
openaire +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
The rise of companies from emerging markets in global health governance: opportunities and challenges [PDF]
, 2014 The article analyses the involvement of pharmaceutical companies from emerging markets in global health governance. It finds that they play a central role as low-cost suppliers of medicines and vaccines and, increasingly, new technologies.
ANNE ROEMER-MAHLER +23 more
core +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
FEATURES OF BUSINESS NEGOTIATIONS IN COMMERCIAL COMPANIES
Proceedings of Scientific Works of Cherkasy State Technological University. Series: Economic Sciences, 2018 In unstable economic conditions for businesses, the need for constructive solution of organizational conflicts between interested parties is of great importance. The need for special management tools that can integrate the goals and interests of all project participants and find an effective way out of conflict situations is emerging.
Kolomytseva, Olena +2 more
openaire +5 more sources
Esterification of Free Fatty Acids with Glycerol within the Biodiesel Production Framework [PDF]
, 2019 Companies in the field of the collection and treatment of waste cooking oils (WCO) for subsequent biodiesel production usually have to cope with high acidity oils, which cannot be directly transformed into fatty acid methyl esters due to soap production.
Carrión Ruiz, Javier +4 more
core +1 more source