Results 111 to 120 of about 1,974,871 (309)
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Ciência Rural: This study was accomplished with the aim to evaluate and to characterize the risks for the presence of Megninia spp. in poultry farms from Minas Gerais, using for that Correspondence Analysis (CA).
Tiago Mendonça de Oliveira +7 more
doaj +1 more source
“An appreciative and grateful author”: Edith Wharton and the House of Macmillan [PDF]
, 2005 This essay is the first piece of scholarship to examine the relationship between the expatriate American novelist Edith Wharton (1862-1937) and her chief British publisher, Macmillan and Co.
Towheed, Shafquat
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin +11 more
wiley +1 more source
Fluid flow analysis by a modified, white light, Lau interferometer [PDF]
, 2002 This paper presents a sharp focussing schlieren system based upon a modified Lau interferometer. A method of reducing the depth of focus of the system is demonstrated and the development of the system to study large fields of view by theincorporation of ...
Mair, L. +4 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung +7 more
wiley +1 more source
Amplifier enhances ring-down spectroscopy [PDF]
, 2004 In recent years, investigators have adapted the principles of ringdown spectroscopy (see sidebar, facing page) to fiber optic configurations by placing high reflectors on each end of a fiber and observing the ringdown time of an injected pulse.
Hitz, B., Stewart, G.
core +1 more source
Variably Protease‐Sensitive Prionopathy: Two New Cases With Motor Neuron‐Dementia Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT We describe two patients with variably protease‐sensitive prionopathy (VPSPr) who developed progressive upper motor neuron symptoms, insomnia, behavioral and cognitive decline, compatible with primary lateral sclerosis associated with frontotemporal dementia (FTD).
María Elena Erro +10 more
wiley +1 more source
Effect of HINS light on the contraction of fibroblast populated collagen lattices [PDF]
, 2009 High intensity narrow spectrum (HINS) light has been shown to have bactericidal effects on a range of medically important bacteria[1]. HINS technology could potentially be useful as a method for disinfecting medical implants, tissue engineered constructs
Anderson, J.G. +4 more
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Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley +1 more source