Results 71 to 80 of about 481,541 (291)

The Social Media Industry as a Commercial Determinant of Health

open access: yesInternational Journal of Health Policy and Management, 2022

Marco Zenone   +2 more
openaire   +4 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Childhood mortality in sub-Saharan Africa : cross-sectional insight into small-scale geographical inequalities from Census data [PDF]

open access: yes, 2012
Objectives To estimate and quantify childhood mortality, its spatial correlates and the impact of potential correlates using recent census data from three sub-Saharan African countries (Rwanda, Senegal and Uganda), where evidence is lacking.
Clarke, Aileen   +2 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Ultra-Processed Food: The Tragedy of the Biological Commons [PDF]

open access: yesInternational Journal of Health Policy and Management, 2023
Norah Campbell   +4 more
doaj   +1 more source

The determinants of successful partnering: a transaction cost perspective [PDF]

open access: yes, 2006
Support is emerging for the assertion that partnering can have a significant beneficial influence on project relationships and project outcomes. However, not all of the evidence bears this out: there are some examples of less-than-successful experiments ...
Greenwood, David, Yates, D. J.
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

A call to advance and translate research into policy on governance, ethics, and conflicts of interest in public health: the GECI-PH network

open access: yesGlobalization and Health, 2021
Efforts to adopt public health policies that would limit the consumption of unhealthy commodities, such as tobacco, alcohol and ultra-processed food products, are often undermined by private sector actors whose profits depend on the sales of such ...
Rima Nakkash   +6 more
doaj   +1 more source

Scope for rotavirus vaccination in India: revisiting the scientific evidence.

open access: yes, 2011
Rotavirus vaccines have been developed to prevent deaths resulting from severe diarrhea of rotavirus origin. The use of vaccines as an intervention at scale to prevent and control the burden of rotavirus diarrhea is supported by the argument that ...
Hasan, Habib   +3 more
core   +1 more source

Informing the ‘early years’ agenda in Scotland: understanding infant feeding patterns using linked datasets [PDF]

open access: yes, 2013
Background: Providing infants with the ‘best possible start in life’ is a priority for the Scottish Government. This is reflected in policy and health promotion strategies to increase breast feeding, which gives the best source of nutrients for healthy ...
Ajetunmobi, Omotomilola   +5 more
core   +1 more source

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