Results 71 to 80 of about 143,771 (314)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

The Bioeconomic Implications of A Bycatch Reduction Device as a Stock Conservation Management Measure [PDF]

open access: yes
The proposed regulation to reduce bycatch and discarding of finfish in the southeastern region is a gear modification that excludes finfish from shrimp trawls.
Ward, John M.
core   +1 more source

Trouble in the Caribbean: Responses to a Potential Chinese-Bahamian Bilateral Fishing Agreement [PDF]

open access: yes, 2018
As of 2011, the Caribbean Sea was one of the only fisheries unoccupied by China’s Distant Water Fleet (DWF). However, in 2016, officials from the People’s Republic of China and the Bahamas discussed a proposal for a bilateral commercial fishing agreement
Elliott, Kyle
core   +1 more source

At-vessel fishing mortality for six species of sharks caught in the northwest Atlantic and Gulf of Mexico [PDF]

open access: yes, 2007
From 1994-2005 the Commercial Shark Fishery Observer Program (CSFOP) placed fishery observers aboard US bottom longline vessels engaged in directed fishing for sharks in the region from New Jersey to Louisiana, USA.
Burgess, George H., Morgan, Alexia
core   +2 more sources

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Distribution of red deepsea crab (Chaceon quinquedens) by size and sex in the Gulf of Mexico [PDF]

open access: yes, 2008
The red deepsea crab (Chaceon quinquedens (Smith, 1879)) has supported a commercial fishery off the coast of New England since the 1970s (Wigley et al., 1975) and has had annual harvests from 400 metric tons (t) (1996) to 4000 t (2001) (NEFMC, 2002). In
Kilgour, Morgan J., Shirley, Thomas C.
core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

The precautionary approach and the management of the European eel (Anguilla anguilla) – critical remarks [PDF]

open access: yes, 2007
Recruitment and commercial catches of European eel have been in decline since the late 1970s. So far, the reasons are not well understood. A range of potential natural and anthropogenic reasons have been discussed, but the relative importance of the ...
Wysujack, Klaus
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

The impact of high commercial fishery load on biological indices of the roach (Rutilus rutilus)

open access: yesVìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Ekologìâ, 2015
Age composition, length and weight indices of the roach populations (Rutilus rutilus L.) were analyzed and compared in water bodies with the different commercial fishery loading levels.
G. O. Kotovska   +2 more
doaj   +1 more source

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