Results 151 to 160 of about 186,062 (250)

A Fish MDA5 Integrates Canonical RIG‐I and MDA5 Ligand Recognition

open access: yesAdvanced Science, EarlyView.
These results show that the large yellow croaker lacks RIG‐I, yet its MDA5 senses both 5′ppp‐dsRNA and long dsRNA. A flexible RNA‐capping loop in the MDA5 C‐terminal domain enables two ligand‐binding modes. This dual recognition signals through MAVS–STING–TBK1/IRF3 and induces type I interferons, revealing unexpected plasticity in vertebrate antiviral ...
Wenxing Li   +7 more
wiley   +1 more source

Women's exposure to commercial milk formula marketing: a WHO multi-country market research study. [PDF]

open access: yesGlobal Health
Horwood C   +6 more
europepmc   +1 more source

Chrysanthemum Morifolium–Derived Nanovesicles Reduce Lactate‐Associated Histone Lactylation and Modulate Microglia‐Mediated Neuroinflammation in Sepsis‐Associated Encephalopathy

open access: yesAdvanced Science, EarlyView.
When used to treat sepsis‐associated encephalopathy, Chrysanthemum morifolium–derived nanovesicles can inhibit the H3K18la/NF‐κB axis to regulate microglia‐mediated neuroinflammation. ABSTRACT Sepsis‐associated encephalopathy (SAE)—a complication of the central nervous system in patients with sepsis—markedly diminishes cognitive functions and is linked
Kaiqiang Li   +11 more
wiley   +1 more source

Donor‐Cell Senescence Redirects PINK1‐Marked Mitochondrial Cargo From Mitophagy to Microvesicle Transfer Through SUMO3‐Stabilized HSPA9

open access: yesAdvanced Science, EarlyView.
ABSTRACT Extracellular vesicle therapies have been developed for tissue repair, but how donor‐cell senescence reshapes vesicle‐mediated mitochondrial transfer remains unclear. Here, we show that senescent adipose‐derived stem cells (ADSCs) redirect damaged mitochondria into microvesicles (MVs), converting protective vesicles into pro‐degenerative ...
Zixuan Ou   +21 more
wiley   +1 more source

Research on commercial milk formulas for young children: A scoping review. [PDF]

open access: yesMatern Child Nutr
Cavalcanti MB   +3 more
europepmc   +1 more source

Aflatoxin in commercial milk samples.

open access: yesSouth African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1968
I F, Purchase, L J, Vorster
openaire   +1 more source

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