Results 181 to 190 of about 186,062 (250)

A Citrulline‐Functionalized Patch Coordinates Macrophage NRF2 Signaling and Arginine Metabolism for Tendon‐to‐Bone Repair

open access: yesAdvanced Science, EarlyView.
A locally implanted patch combines citrulline‐functionalized carbon dots, a thioketal‐containing membrane coating from tendon‐derived stem cells, and aligned core–shell fibers. In macrophages, the patch reduces inflammatory markers and enhances antioxidant signaling through nuclear factor erythroid 2‐related factor 2 (NRF2); in rats and rabbits, it ...
Yuhao Yu   +13 more
wiley   +1 more source

A Bioengineered Mitochondrial Respiration‐Mimetic Copper‐Based Metal‐Organic Framework Reprogramming Oxidative Phosphorylation to Enhance Tumor Cuproptosis

open access: yesAdvanced Science, EarlyView.
A bioengineered mitochondrial respiration‐mimetic nanoplatform (TC@OMG) renews tumor mitochondrial metabolism to enhance cuproptosis. TC@OMG integrates a copper‐based metal‐organic framework co‐loaded with glucose oxidase and a lactate dehydrogenase inhibitor, and is cloaked with a hybrid membrane derived from tumor cells and plant thylakoids, enabling
Liyang Zhou   +7 more
wiley   +1 more source

Pharmacokinetic Tuning Redirects β‐Lapachone From NQO1 Bioactivation to Vimentin‐Targeted Oxidation in Cancer

open access: yesAdvanced Science, EarlyView.
Pharmacokinetic tuning acts as a programmable mechanistic switch for β‐lap. Sustained low‐concentration exposure redirects β‐lap from NQO1 bioactivation to direct oxidation of vimentin, driving disulfide crosslinking, proteasomal overload and ferroptosis.
Lei Dou   +5 more
wiley   +1 more source

Poor chemical and microbiological quality of the commercial milk thistle-based dietary supplements may account for their reported unsatisfactory and non-reproducible clinical outcomes. [PDF]

open access: yesSci Rep, 2019
Fenclova M   +9 more
europepmc   +1 more source

Does a Specialized Niche Market Vegetable Processor Enjoy Bargaining Power?

open access: yesAgribusiness, EarlyView.
ABSTRACT Agribusiness companies may achieve competitive advantage through specialization within niche markets. One such niche is the fresh‐cut fruit and vegetable market, which has been steadily growing in Germany. This study examines whether the specialization of a German fresh‐cut producer grants it with market power within this niche market.
Nikolas Bublik   +3 more
wiley   +1 more source

"I could not find the strength to resist the pressure of the medical staff, to refuse to give commercial milk formula": a qualitative study on effects of the war on Ukrainian women's infant feeding. [PDF]

open access: yesFront Nutr
Iellamo A   +12 more
europepmc   +1 more source

Pricing Dynamics in the US Hemp Market: A Vertical Price Transmission Analysis of the Hemp Value Chain

open access: yesAgribusiness, EarlyView.
ABSTRACT The US hemp market is a new and nascent industry that has been devoid of research for about half a century. This study examined the effects of exogenous shock on price at each phase of the value chain—Farm (hemp biomass), and its impact on prices at other phases of the value chain—Intermediary Processor (crude cannabidiol hemp) and Final ...
Solomon Odiase   +2 more
wiley   +1 more source

Exploring the Impact of Meat Alternative Labeling Regulations on the U.S. Meat Consumption Patterns

open access: yesAgribusiness, EarlyView.
ABSTRACT The global demand for conventional meat continues to rise, but it is also associated with substantial environmental and health challenges. In response, meat alternatives have gained popularity, sparking debates over meat alternative labeling regulations. This study investigates the effects of meat alternative labeling regulations in the United
Jeong Hun Ji, Sang Hyeon Lee
wiley   +1 more source

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