Results 51 to 60 of about 559,239 (237)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

On the Problems of Realization of the Law of the RSFSR «On the Rehabilitation of Repressed Peoples» in the Chechen Republic

open access: yesOriental Studies, 2018
The article deals with the problems of the realization of the law «On the Rehabilitation of Repressed Peoples» in the Chechen Republic. It is noted that in a accordance with the law a number of actions for the restoration of the rights of the Chechen ...
S. Tsutsulaeva, A. Osmaev
doaj  

HOW TO DETERMINE THE AMOTIZED COST OF BANK CREDITS ACCORDING TO THE EFFECTIVE INTEREST RATE METHOD IN THE CONTEXT OF TRANSITION TO IFRS (INTERNATIONAL FINANCIAL REPORTING STANDARDS) [PDF]

open access: yesScientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2013
It is known that licensed banks in the Republic of Moldova are in the period of fulfilling the action plan with a view to implementing the project on transition from the National Accounting Standards to the International Financial Reporting Standards ...
Tatiana SEVCIUC
doaj  

Cities' Legal Actions in the EU: Towards a Stronger Urban Power?

open access: yesEuropean Papers, 2020
(Series Information) European Papers - A Journal on Law and Integration, 2019 4(3), 861-870 | European Forum Insight of 21 February 2020 | (Table of Contents) I. Facts and history of the procedure: a step forward in the so-called dieselgate saga.
Elisabetta Tatì
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Table ronde sur l’histoire de la commission sportive du Parti communiste français

open access: yesCahiers d’histoire, 2013
Si certains journalistes ont pu constater, lors de la dernière campagne présidentielle, que le Front de gauche était « en pointe sur le sujet » du sport, par ailleurs largement délaissé par les autres formations politiques1, l’intérêt du Parti communiste
Yvon Adam   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

«The shameful proposal to return to the motherland…»: declaring bolshevik diplomacy of amnesty in the camp of interned soldiers-ukrainians Kalisz, Poland (1922)

open access: yesЄвропейські історичні студії, 2018
The article reproduces events, which took place on the eve of and during the announcement by the Polish-Soviet delegation of two amnesties in the camp of interned Ukrainian soldiers Kalisz (Poland) in 1922.
Іhor Sribnyak
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Property rights of creditors of a legal entity that is in the process of termination

open access: yesТеорія і практика правознавства, 2018
The article reveals the problem of protection of the rights of creditors upon termination of a legal entity through its reorganization. Since the contractual relationship is an obligation, the property right of the creditor is the right to demand from ...
O. A. Surzhenko
doaj   +1 more source

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