Results 51 to 60 of about 76,017 (307)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

THE LUNACY COMMISSION. [PDF]

The Lancet
n ...
Alderson, J. S., Begley, W. C., Boyd, Robert, Broadhurst, J., Bucknill, J. C., Bush, W. M., Conolly, John, Corsellis, C. C., de Vitre, E. D., Hitchman, John, Holland, John, Huxley, JamesE, Jones, GeoT, Kirkman, J., Ley, W.-M., Mallam, Rich, Morison, A., Nesbitt, P. R., Oliver, Richard, Prosser, H. F., Stewart, Robert, Sutherland, A. J., Thompson, SamuelS, Thurnam, John, Tyerman, D. T., Walsh, F. D., Loyd Williams, R., Williams, J. C., Wintle, F. T., Wilkes, James, Hitch, Samuel, Williams, W. W.   +31 more
openaire   +3 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Commissioning of Building HVAC Systems for Improved Energy Performance: A Summary of Annex 40 Results [PDF]

, 2004
Annex 40 is an international research project which aims at developing, validating and documenting tools for commissioning of buildings and building services.
Visier, J. C.
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Realising the open virtual commissioning of modular automation systems [PDF]

, 2011
To address the challenges in the automotive industry posed by the need to rapidly manufacture more product variants, and the resultant need for more adaptable production systems, radical changes are now required in the way in which such systems are ...
Jain, Atul, Lee, Leslie J., Robert Harrison (263043), Park, Y., Harrison, Robert, Leslie J. Lee (7204337), Kong, Xiangyu, Bilal Ahmad (773365), Xiangjun Kong (145590), Ahmad, Bilal, Atul Jain (827616), Y. Park (7208792)   +11 more
core  

Adaptability evaluation of the software for transient process simulation of supercritical CO2 pipelines

You-qi chuyun
Objective Transient processes like leakage and commissioning in CO2 pipeline operation pose simulation challenges due to the unique physical properties and phase behavior of CO2.
Xinyuan MA, Xin OUYANG, Jianlu ZHU, Junwen CHEN, Luoqian LIU, Teng YANG, Guangchun SONG   +6 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A BEMS-Assisted Commissioning Tool to Improve the Energy Performance of HVAC Systems [PDF]

, 2003
The evolving capabilities of Building Energy Management Systems (BEMS) offer new opportunities to automate some parts of the commissioning process and can generate benefits over the entire life of a building. These benefits include a reduction of process
Corsi, M., Choiniere, D.
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source