Results 141 to 150 of about 341,884 (244)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Barriers and facilitators to knowledge translation at the science-policy interface during the COVID-19 pandemic public health emergency: a rapid review and theoretical analysis to inform development of a logic model. [PDF]

BMC Public Health
Porter AV, Joseph-Williams N, Leighton C, Gal M, Edwards A, Cooper A.   +5 more
europepmc   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Ethical guidelines for geoprivacy: a framework for researchers and ethics committees. [PDF]

Int J Health Geogr
Malekzadeh M, Kestens Y, Blanford JI, Perchoux C, Mostafavi MA, McKenzie G, Kim EK.   +6 more
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

From the "Dark Days" to Golden Days: Lessons From the Botswana National Validation Committee's Journey on the Path to Elimination of Vertical Transmission of HIV. [PDF]

J Int AIDS Soc
Matshaba M, Nthusang Q, Setswalo J, Madidimalo T, Nkomo B, Molefi M.   +5 more
europepmc   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Connections between science and care within public and global health research: the need for attention and action. [PDF]

J Glob Health
Pickersgill M, Abbott C, Campbell H, Chiumento A, Crompton CJ, Fletcher-Watson S, Hanlon C, Jackson T, Mehendale FV, Shi T, Stenhouse R, Waggoner MR, Wild S.   +12 more
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Correction: A collaborative approach of finite element method and machine learning algorithms for biomechanical analysis of implants used in tibial shaft fractures. [PDF]

BMC Musculoskelet Disord
Mutu HB.
europepmc   +1 more source