Results 71 to 80 of about 8,737,527 (299)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

OPTIMASI COMMON MODE REJECTION RATIO (CMRR) PADA PENGUAT INSTRUMENTASI

Jurnal Fisika Flux, 2017
yang sering ada dalam rangkaian sistem sensor. Sinyal keluaran dari sensor biasanya sangat kecil sehingga perlu penguatan untuk dapat terbaca pada rangkaian selanjutnya.
Ahmad Rahimi, Iwan Sugriwan, Tetti Novalina Manik   +2 more
doaj   +3 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Common mode voltage in a motor drive system with PFC

, 2010
Common mode voltage generated by a power converter in combination with parasitic capacitive couplings is a potential source of shaft voltage in an AC motor drive system.
Adabi Firouzjaee, Jafar, Nami, Alireza, Ghosh, Arindam, Adabi, J., Nami, A., Firuz Zare, Zare, Firuz, Arindam Ghosh, Alireza Nami, zare, F., Jafar Adabi   +10 more
core   +1 more source

Performance optimization aspects of common mode chokes [PDF]

, 2007
Optimization aspects of common mode chokes are presented. These are based on a behavioral model for common mode chokes and its sensitivity study. Results are used to show the influence of the designable parameters on the final performance of the choke ...
Hans Bergsma, Roc'h, Anne, Leferink, Frank; id_orcid, Dongsheng Zhao, Bergsma, Hans, Braham Ferreira, Zhao, Dongsheng, Ferreira, Braham, Anne Roc'h, Frank Leferink   +9 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

High-Frequency Induction Drive Analysis for Common Mode and Differential Mode Impedance Characteristics

Eng
The parasitic currents issue arises in induction machines operating at higher frequencies. The parasitic current flow is the main cause of premature degradation of winding insulation deterioration and bearing damage.
Kashif Imdad, Humayun Salahuddin, Zeeshan Ahmad Arfeen, Ghulam Amjad Hussain, Zeeshan Rashid, Nusrat Husain, Muhammad Salman Saeed   +6 more
doaj   +1 more source

Common-Mode Stability Test and Design Guidelines for a Transformer-Based Push-Pull Power Amplifier

IEEE Access, 2020
We report design guidelines for a transformer-based push-pull power amplifier (PA) with a systematic stability test carried out in the complex frequency domain.
Van-Son Trinh, Jung-Dong Park
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source