Results 91 to 100 of about 497,195 (287)
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Active cancellation of the common‐mode voltage produced by a voltage‐source PWM inverter
This paper proposes an “active common-mode noise canceler” that is capable of eliminating the common-mode voltage produced by a voltage-source PWM inverter. It generates a compensating voltage which has the same amplitude as, but the opposite phase to, the common-mode voltage produced by the PWM inverter. The compensating voltage is superimposed on the
Satoshi Ogasawara +2 more
openaire +2 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
The presence of low frequency components in the common mode voltage can cause harmful electromagnetic interference. A critical study on various causes of low frequency components in the common mode voltage of a space vector pulse width modulated Quasi–Z–
Nanda Debalina +2 more
doaj +1 more source
Flexible Common-Mode Voltage Modulation Strategy for Differential Boost Inverters
Photovoltaic power generation and energy storage technology are current hotspots in the clean energy industry. As a core piece of equipment, an inverter is subjected to higher demands for its voltage regulation range and output performance.
Zhaozhe Deng +5 more
doaj +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Space-Vector PWM With Common-Mode Voltage Elimination for Multiphase Drives
Switching common-mode voltage (CMV) generated by the pulse width modulation (PWM) of the inverter causes common-mode currents, which lead to motor bearing failures and electromagnetic interference problems in multiphase drives. Such switching CMV can be reduced by taking advantage of the switching states of multilevel multiphase inverters that produce ...
Oscar Lopez +8 more
openaire +3 more sources
Low power LVDS transceiver for AER links with burst mode operation capability [PDF]
This paper presents the design and simulation of an LVDS transceiver intended to be used in serial AER links. Traditional implementations of LVDS serial interfaces require a continuous data flow between the transmitter and the receiver to keep the ...
Linares Barranco, Bernabé +2 more
core
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source

