Results 21 to 30 of about 3,027 (217)

Exploring an Alternative to mRNA Vaccine Cold Chain Storage: MRNA‐Lipid Nanoparticle Stability When Dried in a Polymer Matrix

Advanced Functional Materials, EarlyView.
The nanostructure, size, and function of mRNA‐loaded lipid nanoparticles are evaluated before drying, within polymer microneedles, and after rehydration. The results reveal the polymer and LNP loadings required to recover nanostructure and preserve the delivery performance in dry‐state formulations.
Brendan P. Dyett, Shahad K. Alsaiari, John L. Daristotle, Timothy A. Forster, Alicia Lau, Dhruv Varshney, Rania Afaneh, Andrew R. Hanna, Charles Sloane, David Mankus, Haitao Yu, Jiali Zhai, DongSoo Yun, Lisa H. Tostanoski, Abigail Lytton‐Jean, Dan H. Barouch, Charlotte E. Conn, Robert Langer, Ana Jaklenec, Calum J. Drummond   +19 more
wiley   +1 more source

Active Common-Mode Voltage Reduction in a Fault-Tolerant Three-Phase Inverter

, 2016
A fault-tolerant topology in a three-phase four-leg inverter which is capable of reducing the common-mode voltage (CMV) during the post-fault condition is presented. The CMV during both post-fault and pre-fault is investigated.
Danyal Mohammadi, Said Ahmed-Zaid, Ahmed-Zaid, Said, Mohammadi, Danyal   +3 more
core   +1 more source

Spontaneous Helical Alignment of Smooth Muscle Cells to Form a Medial Layer for Engineered Microvasculature

Advanced Healthcare Materials, EarlyView.
Spontaneous helical alignment of smooth muscle cells is induced within resistance‐vessel‐sized channels patterned within a hydrogel. The extent of the cells’ orientation angle is dependent on the presence and composition of ECM proteins lining the channel wall and cell seeding density.
Victoria D. Vest, Katherine J. Young, Isabella K. Holtz, Mark Mc Veigh, James D. West, Leon M. Bellan   +5 more
wiley   +1 more source

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

Advanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino, Lucia Pappagallo, Francesca De Chirico, Luca Boselli, Hazem Ahmed, Luca Spagnoletti, Giovanni Pittaluga, Paolo Emidio Costantini, Matteo Calvaresi, Pier Paolo Pompa, Alberto Danielli, Fabio Benfenati, Valentina Castagnola   +12 more
wiley   +1 more source

Novel High Efficiency H-Bridge Transformerless Inverter for Grid-Connected Single-Phase Photovoltaic Systems [PDF]

, 2018
© 2018 IEEE. This paper proposes a new H-bridge type transformerless inverter for grid-connected photovoltaic (PV) application. The proposed H-bridge zero voltage switch controlled rectifier (HB-ZVSCR) inverter uses additional switches and diodes at the ...
Siwakoti, YP, Li, L, Forouzesh, M, Khan, MNH   +3 more
core   +1 more source

Conductive Hydrogels for Exogenous Sensing and Cell Fate Control

Advanced Materials, EarlyView.
We engineer electrically conductive hydrogels by combining sulfated glycosaminoglycans with semiconducting polymers. These hydrogels bind bioactive proteins, including growth factors, whose release or retention can be modulated by low‐voltage stimulation. The hydrogels are also integrated as 3D channels in organic electrochemical transistors as part of
Teuku Fawzul Akbar, Carlos Alejandro Jimenez‐Rodriguez, Railia Biktimirova, Ilka Hermes, Thomas Kurth, My Duyen Pham, Mikhail Tsurkan, Jens Friedrichs, Francis L. C. Morgan, Hans Kleemann, Olga Guskova, Uwe Freudenberg, Peter Fratzl, Carsten Werner, Christoph Tondera, Ivan R. Minev   +15 more
wiley   +1 more source

Common-Mode Voltage Elimination of Multilevel Converters With Reduced Switching Loss Using Sawtooth-Carrier-Based PWM

, 2023
This article proposes an asymmetrical switching pattern to eliminate common-mode voltage (CMV) in multilevel converters while reducing switching loss by rearranging the switching sequence to minimize the number of level-shifts.
Ximei Liu, Decun Niu, Lei Zhang, Minghao Chen, Niu, Decun, Liu, Ximei, Chen, Minghao, Zhang, Lei   +7 more
core   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

CMV analysis of 5-level Cascaded H-Bridge MLI with equal and unequal DC Sources using Variable frequency SPWM Techniques

, 2019
This paper, investigates the Common Mode Voltage (CMV)between neutral point of the star connected RL load and system ground.CMV also known as zero sequence voltage results in adverse effects like bearing currents, shaft voltages and electromagnetic ...
Mohd Esa (6267437)
core   +1 more source

One Cycle Control of a PWM Rectifier a New Approach

, 2020
This paper analyzes a Digital Signal Processor (DSP) based One Cycle Control (OCC) strategy for a Power Factor Corrector (PFC) rectifier with Common-mode Voltage (CMV) immunity. It is proposed a strategy that utilizes an emulated-resistance-controller in
Joao T. Carvalho Neto, Andrés O. Salazar, Guilherme A. P. De C. A. Pessoa, Elmer R. L. Villarreal, Werbet L. A. Silva, Rodrigo De A. Teixeira, Alberto S. Lock   +6 more
core   +1 more source