Results 201 to 210 of about 7,832,169 (352)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Ultrasound-Assisted Enzymatic Hydrolysates from Common Bean and Pumpkin Seed Proteins: Antioxidant and Anti-Inflammatory Properties. [PDF]

Antioxidants (Basel)
Huerta-Rodriguez E, Sanchez-Jimenez O, Chuck-Hernández C, Martinez-Fierro ML, Garza-Veloz I, Cárdenas-Chávez DL, Ponce-Ponce de Leon CA, Rocha-Pizaña MDR.   +7 more
europepmc   +1 more source

June 3, 1901: Common Council, Regular Session

, 1899
Common Council, Indianapolis
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Functional Outcomes of Arthroscopic Anterior Cruciate Ligament Reconstruction Using Hamstring Tendon Autograft in a Predominantly Chronic Anterior Cruciate Ligament Injury Cohort: A Prospective Study. [PDF]

J Orthop Case Rep
Grover K, Khajotia BL, Sharma V, Shibu MK, Singh N.   +4 more
europepmc   +1 more source

March 3, 1879: Common Council, Regular Session

, 1878
Common Council, Indianapolis
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Comprehensive genotype-phenotype correlation analysis in 11 509 neonates carrying common deafness-associated pathogenic variants. [PDF]

J Med Genet
Li J, Zhan Z, Zhang X, Wu B, Liu W.
europepmc   +1 more source

October 3, 1887: Common Council, Regular Session

, 1887
Common Council, Indianapolis
core