Results 111 to 120 of about 4,963,534 (306)

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

Determination of Diameter and Angulation of the Normal Common Bile Duct using Multidetector Computed Tomography

Gut and Liver, 2009
Background/AimsCommon bile duct stones are associated with the extent of dilation of the common bile duct as well as its angulation. Multidetector computed tomography (MD CT) has a good resolution for the definition of the anatomical features of the ...
doaj   +1 more source

Presence of choledocholithiasis in patients undergoing cholecystectomy for mild biliary pancreatitis

Journal of Society of Surgeons of Nepal, 2016
Introduction: Standard recommendations for patients recovering from an episode of biliary pancreatitis include cholecystectomy with intra operative cholangiogram or ERCP during the same hospital admission as it is believed that the instigating factor is ...
S Pradhan, S Shah, S Maharjan, JN Shah
doaj   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Utility of Common Bile Duct Identification on Biliary Ultrasound in Emergency Department Patients [PDF]

Christopher Thom, Justin Yaworsky, Kevin Livingstone, David Han, Jakob Ottenhoff Department of Emergency Medicine, University of Virginia Health System, Charlottesville, Virginia, USACorrespondence: Christopher Thom, University of Virginia Health System,
Thom C, Yaworsky J, Livingstone K, Han D, Ottenhoff J   +4 more
core  

Variant Anatomy Literacy as a Patient‐Safety Competency in Surgical Training: A Title‐Informed Conceptual Review and Competency Framework

Clinical Anatomy, EarlyView.
ABSTRACT Surgical safety depends on recognition of patient‐specific anatomy when encountered structures depart from population norms. Knowledge of anatomical variations is often treated as supplemental rather than as a safety‐relevant necessity.
Juan A. Sanchis‐Gimeno, Andreea‐Bianca Zuld, Mathias Orellana‐Donoso, Juan José Valenzuela‐Fuenzalida, Guinevere Granite   +4 more
wiley   +1 more source

Evaluation of Clinical Indications of Three Treatments for Choledocholithiasis with Acute Cholangitis

International Journal of General Medicine, 2023
Ling Chen,1 Zujian Wu,1 Chi Guo,1 Guoping Wang,1 Kui Tu,2 Jichang Jiang2 1General Surgery, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang Province, 310012, People’s Republic of China; 2General Surgery, Affiliated Hospital of Zunyi Medical ...
Chen L, Wu Z, Guo C, Wang G, Tu K, Jiang J   +5 more
doaj  

Maternal and Neonatal Complications Associated with Breast Cancer Systemic Treatments—A VigiBase Disproportionality Analysis Study

Clinical Pharmacology &Therapeutics, EarlyView.
Pregnancy‐associated breast cancer (PrBC) presents therapeutic challenges. Understanding maternal–fetal safety of systemic anticancer therapies is critical. We performed a case/non‐case disproportionality analysis using the WHO global pharmacovigilance database up to January 2024, to evaluate maternal–fetal outcomes associated with breast cancer (BC ...
Rayan Kabirian, Floriane Jochum, Elise Dumas, Florence Coussy, Kevin Bihan, Bénédicte Lebrun‐Vignes, Barbara Pistilli, Marc‐Antoine Benderra, Lise Selleret, Laurent Chouchana, Fabien Reyal, Anne‐Sophie Hamy, Paul Gougis   +12 more
wiley   +1 more source

Congenital double bile duct presenting as recurrent cholangitis in a child

Journal of Pediatric Surgery Case Reports, 2015
Double common bile duct (DCBD) is a rare congenital anomaly. Most of these bile duct anomalies are associated with bile duct stones, anomalous pancreaticobiliary junction (APBJ), pancreatitis and bile duct or gastric cancers.
K.D. Chakravarty, Jaya Agarwal, A.C. Praveen Kumar   +2 more
doaj   +1 more source