Post-cholecystectomy Cystic Duct Stump Calculus With Cystic Duct Remnant-Common Bile Duct Fistula Causing Choledocholithiasis: A Report of a Rare Case. [PDF]
Khan MA, Shaikh AR, Jha VP, Kumar A.
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Pufferfish exposure and presumed tetrodotoxicosis in Australian dogs: 372 cases (2007–2018)
Introduction Tetrodotoxin (TTX) is a neurotoxin found in pufferfish that results in the blockade of excitatory conduction and clinical signs including gastrointestinal upset and paralysis. The objectives of this study were to describe the epidemiology of pufferfish exposure and presumed tetrodotoxicosis in dogs, and to determine associations with the ...
J Hanson, CR Sharp, EM Leister
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Tuberculous Peripancreatic Lymphadenitis Presenting as Obstructive Jaundice Due to Extrinsic Common Bile Duct Compression: A Case Report. [PDF]
Al Hariri B, Nashwan AJ.
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Background and Purpose Metabolic dysfunction‐associated steatohepatitis (MASH) is linked to activation of hepatic stellate cells (HSCs) to α‐smooth muscle actin–positive myofibroblasts that produce collagen and proinflammatory cytokines. Quiescent HSCs express the NO‐cGMP signalling axis.
Krithika Rajeeth +14 more
wiley +1 more source
Laparoscopic minimal incision at cystic duct confluence for common bile duct stones in patients with thin-caliber bile ducts: A retrospective comparative study. [PDF]
Huang Y, Xie J, He G.
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MTAP Deficiency as a Metabolic Vulnerability in Cancer: Implications for Synthetic Lethal Therapy
MTAP deletion creates a therapeutically actionable metabolic vulnerability through MTA accumulation and PRMT5 dependency. This review summarizes the biochemical basis of MTAP‐directed synthetic lethality, emerging PRMT5/MAT2A inhibitors, clinicogenomic features of MTAP‐deleted tumors, and future strategies for precision oncology.
Hiroaki Ikushima, Hidenori Kage
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Temporary sphincter-preserving covered biliary stent with a frontal umbrella-shaped occlusive mechanism for common bile duct stone removal. [PDF]
Zhang W +5 more
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Bile‐derived exosomal miR‐196a and miR‐196b are identified as novel biomarkers for biliary tract cancer. Serum miR‐196a levels are significantly elevated in advanced disease with metastasis, while both miRNAs contribute to tumor progression by promoting cancer cell proliferation and invasion.
Naotaka Kugiyama +20 more
wiley +1 more source
GEVIS: A Workflow‐Driven Visual Analytics Approach to Differential Gene Expression Analysis
Abstract Differential gene expression (DGE) analysis is one of the most widely used techniques for investigating RNA‐seq data and supports numerous medical and biological applications, including biomarker identification for diagnosis and prognosis, as well as the evaluation of medical treatments.
G. Blasilli +4 more
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