Results 251 to 260 of about 279,538 (412)

Genome‐wide analysis of somatic noncoding mutation patterns and mitochondrial heteroplasmic shift in type B1 and B2 thymomas

open access: yesThe Journal of Pathology, EarlyView.
Abstract Type B1 and B2 thymomas are lymphocyte‐rich malignant tumours with few somatic mutations in protein‐coding regions of the nuclear genome; nonetheless, noncoding regions remain uncharacterized. Here, we developed a method to isolate pure thymoma cells from lymphocyte‐rich tissues, and then performed genome‐wide deep sequencing. The total number
Kohei Fujikura   +10 more
wiley   +1 more source

Peptidomics in Different Phases of Severe Acute Pancreatitis Model

open access: yesPROTEOMICS – Clinical Applications, EarlyView.
ABSTRACT Severe acute pancreatitis (SAP) involves dynamic shifts from inflammation to immunosuppression, where peptidomic profile evolution may reveal prognostic biomarkers. Here, the plasma peptidome of rats with taurocholate‐induced SAP at 1, 3, 6, 12, and 24 h compared with controls was characterized using nLC‐MS/MS.
Roberto Rasslan   +8 more
wiley   +1 more source

Characterizing Apixaban Pharmacokinetics Through Physiologically‐Based Pharmacokinetic Modeling: Critical Role of Biliary Secretion and Enterohepatic Circulation in Humans

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Apixaban, a factor Xa inhibitor, is a direct oral anticoagulant with a well‐balanced elimination; it is eliminated evenly via feces, urine (with no active secretion), and as metabolites after oral administration. The common understanding is that biliary secretion and enterohepatic circulation (EHC) of apixaban are limited in humans, and that ...
Toshiaki Tsuchitani   +3 more
wiley   +1 more source

The feasibility and safety of laparoscopic transcystic common bile duct exploration after prior gastrectomy

open access: gold
Jian Huang   +8 more
openalex   +1 more source

THE MINOR PAPILLA IN THE DUODENAL DIVERTICULUM: ITS POSSIBLE ETIOLOGICAL ROLE IN THE FORMATION OF COMMON BILE DUCT DILATATION

open access: diamond, 2000
Tetsuo Morishita   +8 more
openalex   +2 more sources

Management of common bile duct stones in the era of laparoscopic cholecystectomy [PDF]

open access: diamond, 2009
Mohammad Zaki Ahmad   +3 more
openalex   +1 more source

Machine Learning‐Based Risk‐Adjusted CUSUM Control Chart for Monitoring Readmission Rate Following PTBD Catheter Placement

open access: yesQuality and Reliability Engineering International, EarlyView.
ABSTRACT Percutaneous transhepatic biliary drainage (PTBD) catheter placement is known to have a high readmission rate. This work focuses on monitoring the change in readmission rate after a new clinical paradigm for post‐procedural care is implemented for the PTBD procedures.
Muhammed Aljifri   +2 more
wiley   +1 more source

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