Transglutaminase‐mediated cytokeratin modifications implicated in bile‐acid‐induced hepatocyte death
Cholestasis and bile‐acid exposure enhance expression and activity of protein crosslinking enzymes TG1 and TG2 in hepatocytes. Substrate proteins were identified by mass spectrometry using biotin‐labeled peptides (pepK5/pepT26) or amine donor (biotinylated pentylamine; BPA). Crosslinking‐induced aggregation and fragmentation of keratin 18 and 8 (K18/K8)
Hideki Tatsukawa +4 more
wiley +1 more source
Efficacy and safety of percutaneous papillary balloon dilation for common bile duct stones: a systematic review and meta-analysis. [PDF]
Sun Y, Wang W, Li Y, Wang W.
europepmc +1 more source
Differentiating intrahepatic CCA from PDAC metastatic to the liver is critical for the clinical management of patients with pancreatobiliary cancers. AQP1 has demonstrated an excellent discriminatory performance in this clinical scenario. Aims Differentiating intrahepatic cholangiocarcinoma (iCCA) from metastatic ductal adenocarcinoma of the pancreas ...
Leoncini Giuseppe +7 more
wiley +1 more source
A novel endoscopic lithotripsy technique for a huge common bile duct stone: endoscopic snare lithotripsy. [PDF]
Tanaka H +5 more
europepmc +1 more source
ABSTRACT Aim To evaluate the impact of multiple apical periodontitis (AP) on the expression of TLR4/NF‐κB pathway components, proinflammatory cytokine levels, and development of hepatic injuries in rats with and without chronic alcohol consumption. Methodology Thirty‐two rats were assigned to four groups (n = 8): Control, AP, Alcohol, and Alcohol+AP ...
Karem Paula Pinto +6 more
wiley +1 more source
Robotic-Assisted Common Bile Duct Exploration for Choledocholithiasis: A Systematic Review and Meta-Analysis of Efficacy and Safety Outcomes. [PDF]
Lee TY +3 more
europepmc +1 more source
Pathogenesis and Therapeutics for Chronic Pruritus of Unknown Origin: A Systematic Review
ABSTRACT Chronic pruritus of unknown origin (CPUO) is a distressing condition characterized by persistent itch lasting over 6 weeks without an identifiable cause. The underlying mechanisms remain poorly understood, complicating diagnosis and treatment.
Yagiz Matthew Akiska +8 more
wiley +1 more source
Small but mighty: cylindrical transparent cap-assisted cholangioscopic electrohydraulic lithotripsy and stone extraction for the treatment of difficult common bile duct stones. [PDF]
Li X, Liu WH.
europepmc +1 more source
Hepatic sepsis: Generally applicable lessons learned from liver transplantation [PDF]
Putnam, CW, Starzl, TE
core
The junction between the midgut and hindgut co‐localizes with the rectosigmoid junction
At 5 weeks of development, the midgut has formed its primary loop (left). It is well established that the midgut is bounded cranially by the caudal end of the ventral mesentery and the presence of the common bile duct, but its caudal boundary remains to be established.
Hui Gao +5 more
wiley +1 more source

