Results 231 to 240 of about 4,973,845 (291)

A Shared Genomic Alteration Supported the Diagnosis of Two Tumors in the Remnant Pancreas 7 Years after Resection of Distal Cholangiocarcinoma. [PDF]

open access: yesSurg Case Rep
Tamura H   +11 more
europepmc   +1 more source

Targeting GALNT7 Disrupts the TAZ O‐GalNAcylation Feedback Loop to Suppress Gallbladder Cancer Progression

open access: yesAdvanced Science, Volume 13, Issue 55, 5 October 2026.
Aberrant GALNT7‐mediated O‐GalNAcylation stabilizes TAZ to drive gallbladder cancer progression through a feed‐forward transcriptional loop. Structure‐based screening identifies Olaparib as a potent GALNT7 antagonist that disrupts this oncogenic axis, providing an immediate therapeutic strategy for this aggressive malignancy.
Peng Qiu   +11 more
wiley   +1 more source

Low Phospholipid‐Associated Cholelithiasis in a Mother–Son Pair Associated With a Novel ABCB4 Frameshift Variant

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Low phospholipid‐associated cholelithiasis (LPAC) syndrome is a rare inherited disorder caused by ABCB4 mutations with heterogeneous manifestations. We describe two LPAC cases in a mother–son pair, detailing their clinical presentations, diagnostic evaluations, and management. A novel ABCB4 frameshift variant (c.715_716insTT; p.Ser239PhefsTer9)
Hui‐Ming Yang, Jun Liu, Zheng Zhang
wiley   +1 more source

Dorsal Pancreatic Agenesis Associated With New‐Onset Diabetes Mellitus and Acute Pancreatitis in an 18‐Year‐Old Man: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Dorsal pancreatic agenesis (DPA) is a rare congenital disorder resulting from failure of development of the dorsal pancreatic bud. Complete DPA implies absence of the pancreatic neck, body, and tail and can be associated with both diabetes mellitus and pancreatitis. The patient was an 18‐year‐old man admitted with a history of epigastric pain,
Mugheesa Rab   +5 more
wiley   +1 more source

Pediatric Superior Mesenteric Artery Syndrome: A Rare Case Report and Literature Review From Sudan

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT A 10‐year‐old Sudanese boy with chronic bilious vomiting, cachexia, and scaphoid abdomen was diagnosed with Superior Mesenteric Artery Syndrome (SMAS) via CT angiography. After failed conservative management, side‐to‐side duodenojejunostomy resolved symptoms.
Alaa Yousif Yagoob Mohammed   +6 more
wiley   +1 more source

Mapping Mutations and Signaling Network Interactions to Guide Precision Therapy in Gallbladder Cancer

open access: yesCancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Gallbladder cancer (GBC) is a biologically complex malignancy arising from the epithelial lining of the gallbladder, with adenocarcinoma constituting the major histological subtype. Early detection is challenging because of vague clinical manifestations and the organ's deep‐seated anatomical location, resulting in diagnosis at ...
Nisha Manav   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy