Results 51 to 60 of about 290,820 (278)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Merger by Migration at the Final Phase of Common Envelope Evolution

, 2012
I find the common envelope (CE) energy formalism, the CE \alpha-prescription, to be inadequate to predict the final orbital separation of the CE evolution in massive envelopes.
Alibert, Artymowicz, Chomiuk, Clayton, De Marco, De Marco, García-Berro, Han, Han, Iben, Ilkov, Ivanova, Ivanova, Kashi, Livio, Livio, Lombardi, Maxted, Nelemans, Nelemans, Nelson, Noam Soker, Paczynski, Passy, Rasio, Sandquist, Soker, Soker, Soker, Soker, Sparks, Taam, Taam, Tauris, Tout, Webbink, Webbink, Xu, Zorotovic   +38 more
core   +1 more source

Radiating the Hydrogen Recombination Energy during Common Envelope Evolution [PDF]

The Astrophysical Journal Letters, 2018
Abstract Using the stellar evolution code Modules for Experiments in Stellar Astrophysics (MESA), we show that most of the hydrogen recombination energy that is released as the envelope expands during a regular common envelope evolution—namely, the initial dynamical phase or plunge-in phase—is radiated, and hence substantially increases ...
Noam Soker, Aldana Grichener, Efrat Sabach   +2 more
openaire   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Two-dimensional Radiation-hydrodynamic Simulations of Luminous Red Novae

The Astrophysical Journal Letters
Luminous red novae (LRNe) are transients associated with mass ejection during stellar mergers and common envelope evolution (CEE). LRNe have the potential to illuminate the poorly understood phases of binary evolution leading up to the CEE, during the ...
Anthony Kirilov, Diego Calderón, Ondřej Pejcha, Paul C. Duffell   +3 more
doaj   +1 more source

ON THE BINDING ENERGY PARAMETER λ OF COMMON ENVELOPE EVOLUTION [PDF]

The Astrophysical Journal, 2010
23 pages, 3 figures, accepted for publication in ApJ.
Xu, Xiao-Jie, Li, Xiang-Dong
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Bridging the Gap between Luminous Red Novae and Common Envelope Evolution: The Role of Recombination Energy and Radiation Force

The Astrophysical Journal Letters
Luminous red novae and their connection to common envelope evolution (CEE) remain elusive in astrophysics. Here, we present a radiation hydrodynamic model capable of simulating the light curves of material ejected during a CEE.
Zhuo Chen, Natalia Ivanova
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

From Common Envelope Evolution to Luminous Red Novae. I. A One-dimensional Radiation Hydrodynamic Model

The Astrophysical Journal
The acceleration and unbinding of the common envelope during the plunge-in phase are governed by complex physical processes that often manifest observationally as luminous red novae.
Zhuo Chen
doaj   +1 more source