This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source
Improved genetic algorithm based on bi-level co-evolution for coverage path planning in irregular region. [PDF]
Chen G+6 more
europepmc +1 more source
COMMON FIXED POINT OF COMPATIBLE MAPS OF TYPE (γ) ON COMPLETE FUZZY METRIC SPACES
Shaban Sedghi+2 more
openalex +2 more sources
Causal Inference in Presence of Intra-Patient Correlation due to Repeated Measurements of Exposure and Outcome in Longitudinal Settings. [PDF]
Gavoille A+5 more
europepmc +1 more source
COMMON FIXED POINT THEOREM OF ALTMAN INTEGRAL TYPE MAPPINGS
Yaqiong Li, Feng Gu
openalex +2 more sources
Understanding and measuring mechanical signals in the tumor stroma
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz+3 more
wiley +1 more source
2D and 3D Scans of Granular Rock Material Heaps and Calibration Models. [PDF]
Klanfar M+3 more
europepmc +1 more source
Mapping Hsp104 interactions using cross‐linking mass spectrometry
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal+3 more
wiley +1 more source
Pseudoaneurysm as a Complication of Femur Fracture Fixation. [PDF]
Elzayat M+4 more
europepmc +1 more source
Necessary and sufficient conditions for common fixed point theorems in fuzzy metric space
Donal O’Regan, Mujahid Abbas
openalex +1 more source