Results 61 to 70 of about 6,369,664 (287)

Total Synthesis of Decahydroquinoline Poison Frog Alkaloids ent-cis-195A and cis-211A

Molecules, 2021
The total synthesis of two decahydroquinoline poison frog alkaloids ent-cis-195A and cis-211A were achieved in 16 steps (38% overall yield) and 19 steps (31% overall yield), respectively, starting from known compound 1.
Takuya Okada, Naizhen Wu, Katsuki Takashima, Jungoh Ishimura, Hiroyuki Morita, Takuya Ito, Takeshi Kodama, Yuhei Yamasaki, Shin-ichi Akanuma, Yoshiyuki Kubo, Ken-ichi Hosoya, Hiroshi Tsuneki, Tsutomu Wada, Toshiyasu Sasaoka, Takahiro Shimizu, Hideki Sakai, Linda P. Dwoskin, Syed R. Hussaini, Ralph A. Saporito, Naoki Toyooka   +19 more
doaj   +1 more source

Thermal Plasticity is Regulated by a Key MicroRNA During Range Expansion of an Invasive Fruit Fly

Advanced Science, EarlyView.
Populations at the invasion front of Bactrocera dorsalis adapt through reduced phenotypic and gene expression plasticity, a phenomenon likely to be driven by genetic assimilation. We identify a key miRNA‐mediated regulatory axis, in which miR‐276b post‐transcriptionally represses thw, a conserved chitin‐binding gene critical to the cold‐tolerance ...
Yan Zhao, Juntao Hu, Juan Du, Shaokun Guo, Youming Hou, Zhihong Li   +5 more
wiley   +1 more source

Do parasitic trematode cercariae demonstrate a preference for susceptible host species? [PDF]

PLoS ONE, 2012
Many parasites are motile and exhibit behavioural preferences for certain host species. Because hosts can vary in their susceptibility to infections, parasites might benefit from preferentially detecting and infecting the most susceptible host, but this ...
Brittany F Sears, Andrea D Schlunk, Jason R Rohr   +2 more
doaj   +1 more source

Assessing the performance of Alphitobius piceus (Oliver, 1792) as novel feeder insect species for small sized postmetamorphic frogs

Studia Universitatis Babeș-Bolyai. Biologia, 2021
One of the major difficulties of frog farming is providing adequate food in the first few weeks after the metamorphosis. This is a critical time frame, with rapid growth and high mortality.
Octavian CRAIOVEANU, Cristina CRAIOVEANU, Mihai-Iacob BENȚEA, Cristian-Ovidiu COROIAN, Vioara MIREȘAN   +4 more
doaj   +1 more source

Responses to nitrate pollution, warming and density in common frog tadpoles ( Rana temporaria )

, 2016
Amphibians face a variety of anthropogenic environmental perturbations that could act alone or in combination to influence population size. We investigated interactive effects of warming conditions, a moderate pulse of nitrogen pollution, and conspecific
Andrés Egea‐Serrano, J. Buskirk
semanticscholar   +1 more source

Engineered Living Systems With Self‐Organizing Neural Networks: From Anatomy to Behavior and Gene Expression

Advanced Science, EarlyView.
Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat, Laurie O'Neill, Léo Pio‐Lopez, Megan M. Sperry, Patrick Erickson, Tiffany Lin, Michael Levin   +6 more
wiley   +1 more source

Prediction of Rail Contact Fatigue on Crossings Using Image Processing and Machine Learning Methods

Urban Rail Transit, 2019
In this paper, an application of computer vision and machine learning algorithms for common crossing frog diagnostics is presented. The rolling surface fatigue of frogs along the crossing lifecycle is analysed.
Mykola Sysyn, Ulf Gerber, Olga Nabochenko, Dmitri Gruen, Franziska Kluge   +4 more
doaj   +1 more source

Toxicity of Bacillus thuringiensis var. israelensis in aqueous suspension on the South American common frog Leptodactylus latrans (Anura: Leptodactylidae) tadpoles.

Environmental Research, 2015
The effects of commercial formulations of Bacillus thuringiensisvar.israelensis (Bti) on non-target organisms are still a matter of debate; in amphibians, the risks of Bti are little known.
R. Lajmanovich, C. Junges, Mariana C. Cabagna-Zenklusen, Andrés M. Attademo, P. Peltzer, Mariana I. Maglianese, V. Márquez, A. Beccaria   +7 more
semanticscholar   +1 more source

Islet Amyloid Polypeptide Modelled to Simulate Diabetes Co‐Oligomerized with β‐Amyloid 1‐42 Reproducing the Pathological Cascade of Alzheimer's Disease in Human Cerebral Organoids

Advanced Science, EarlyView.
Human islet amyloid polypeptide (hIAPP) was used to mimic T2DM, and Aβ42‐hIAPP co‐oligomers were delivered into the human mature cerebral organoids (COs), which reproduce typical AD pathology and significant neuronal death more closely resembling that of AD patients.
Jin Yan, Zhimeng Tang, Yanyu Luo, Bin Liu, Xinxin Huang, Jun Wei, Feng Yue   +6 more
wiley   +1 more source

Local adaptation with high gene flow: temperature parameters drive adaptation to altitude in the common frog (Rana temporaria)

Molecular Ecology, 2014
Both environmental and genetic influences can result in phenotypic variation. Quantifying the relative contributions of local adaptation and phenotypic plasticity to phenotypes is key to understanding the effect of environmental variation on populations.
A. Muir, Roman Biek, R. Thomas, Barbara K. Mable   +3 more
semanticscholar   +1 more source