Results 161 to 170 of about 10,765,825 (287)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

CCG News Issue 10, May 13, 2024

open access: yes
Issue of CCG News, a publication of Peace and Justice Studies at the University of Scranton, in collaboration with Christians for the Common ...
University of Scranton. Christians for the Common Good
core   +1 more source

Citizen data sovereignty is key to wearables and wellness data reuse for the common good. [PDF]

open access: yesNPJ Digit Med
Gilbert S   +4 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

EASE–CEA: an Italian general practice reform model balancing autonomy and accountability in Italy’s primary care

open access: yesFamily Medicine and Community Health
Walter Ricciardi   +3 more
doaj   +1 more source

An open-source platform for pediatric cancer data exploration: a report from Data for the Common Good. [PDF]

open access: yesJAMIA Open
Wyatt KD   +6 more
europepmc   +1 more source

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