Results 51 to 60 of about 2,437,627 (308)
Économie politique de la santé comme bien public mondial
Revue de la Régulation, 2015 This paper explores the relevance of the notion of global public good applied to health. The first section investigates the conceptual ambiguity of health as a global public good. Outlining the coexistence of three approaches, the second section analyses
Bruno Boidin
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Harnessing Social Processes for the Common Good
Journal for Perspectives of Economic Political and Social Integration, 2018 This article argues that harnessing social processes for the common good depends on creating a learning society which will innovate, learn, and evolve in the long-term public interest. In essence, this involves establishing more embedded, interconnected,
Raven John
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Partycypacja obywatelska w demokracji deliberacyjnej ku dobru wspólnemu
Opolskie Studia Administracyjno-Prawne, 2020 The author draws attention to the consideration of the complexity of civil participation in deliberative democracy, indicating that the legislator assumed that dialogue is to be a way of existence, and thus the basis of any social situation in the state.
Stanisław Leszek Stadniczeńko
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The common good of the company and the theory of organization [PDF]
The concept of common good occupies a prominent place in political and social philosophy, yet it has had little impact on the theory of the firm. This is despite some recent attempts to resituate the theory of the firm on broader and therefore more ...
Argandoña, Antonio
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