Results 31 to 40 of about 13,118,097 (330)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

THE APPROACH BETWEEN THE GREATEST SYSTEMS OF CONTEMPORARY LAW

open access: yesRevista Eletrônica de Direito Processual, 2018
The present paper intends to analyse the main aspects of the two greatest families in Law, to conclude that, nowadays, the civil law system does not distance, as much as believed, from common law.
Danilo Candido Portero
doaj   +1 more source

Common law – common mistakes?

open access: yesInternational Journal of Public Sector Management, 2006
PurposeThe paper aims to respond conceptually, rather then empirically, to policy ignorance. It seeks to examine certain aspects of whistleblower protection offered in the common law countries of Australia, New Zealand, South Africa, and the UK.Design/methodology/approachThe paper provides a four‐country comparison of whistleblower protection laws ...
openaire   +3 more sources

Customary International Law Acts As Federal Common Law in U.S. Courts [PDF]

open access: yes, 1996
This Note discusses how international common law should act as federal common law in U.S. courts. This Note also explores the constitutional challenges involved in incorporating customary international law into U.S. federal common law.
Giba-Matthews, F.
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Potential common law liability for privately provided flood defences [PDF]

open access: yes, 2004
Public bodies have no statutory duty to provide flood defences and do not have funds available to meet all requests for them. This had led to recognition that flood prevention is not something to be left to others and there is now encouragement to ...
Wynn, P
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Tendencias actuales del derecho probatorio civil de los Estados Unidos

open access: yesEstudios de Derecho, 2020
El presente artículo aborda las tendencias actuales del derecho probatorio civil en los Estados Unidos a partir de los conceptos fundamentales que lo componen, como son la carga de la prueba, las presunciones, la carga de producción, la carga de ...
Dimaro Alexis Agudelo-Mejía
doaj   +1 more source

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