Results 181 to 190 of about 3,195 (236)

KMT5C‐Mediated H4K20me3 Recruits EWSR1 to Propel Clear Cell Renal Cell Carcinoma Progression via Regulating ACADM Transcription and m6A Modification

Med Research, EarlyView.
A schematic diagram illustrating the KMT5C‐H4K20me3‐EWSR1‐ACADM signaling axis and its role in ccRCC progression. Key Outcomes: KMT5C/H4K20me3 are upregulated in ccRCC and predict poor prognosis. EWSR1 is a novel noncanonical H4K20me3 reader in ccRCC. KMT5C/EWSR1 co‐repress ACADM via transcription and m6A modification. A‐196 + sunitinib synergistically
Chengjian Ji, Da Zhong, Tian Rao, Xiaojun Li, Weiyu Kong, Xi Zhang, Xiyi Wei, Bing Yao, Xinqiang Li, Ninghong Song, Chao Qin   +10 more
wiley   +1 more source

Design and Implementation of a Computer-Controlled Hybrid Oscillatory Ventilator. [PDF]

J Med Device
Cruz AF, Herrmann J, Hajdarevic B, Hawley ML, Fox D, Bates JHT, Kaczka DW.   +6 more
europepmc   +1 more source

An open‐source pipeline for longitudinal single‐cell tracking and cell‐cycle/migration coupling analysis for neurotherapeutic screening

Neuroprotection, EarlyView.
Integrated experimental and computational pipeline for longitudinal single‐cell tracking and cell‐cycle dynamics analysis. Schematic of the FUCCI (Fluorescence Ubiquitination‐based Cell Cycle Indicator) reporter system. The construct is driven by the CAG promoter (CMV enhancer + chicken β‐actin promoter) and encodes two fusion proteins: mKO2‐Cdt1 ...
Neha Chandra, Matthew Yang, Hailey Wang, Miroslaw Janowski, Piotr Walczak, Cedric Allier, Yajie Liang   +6 more
wiley   +1 more source

Pilot longitudinal integrated transcriptomic-metabolomic study reveals immune and metabolic signatures in non-hospitalized healthcare workers with long COVID. [PDF]

Front Cell Infect Microbiol
Espín E, Yang C, Shannon CP, Checkervarty AK, Kim S, Lapp L, Assadian S, Grunau B, Goldfarb DM, Hutton J, Huan T, Tebbutt SJ.   +11 more
europepmc   +1 more source

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

Prenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell, Samantha Stover, Nora Gibson, Timothy Olson, James Connelly, Matthew Grace, Jennifer Andrews   +6 more
wiley   +1 more source

A Framework for Evaluation of New Processing Technologies in Human Milk Banking. [PDF]

Compr Rev Food Sci Food Saf
Clifford V, Walter L, Klein LD, Wu T, Wang Y, Bansal N.   +5 more
europepmc   +1 more source

Long‐term outcomes of haploidentical hematopoietic stem cell transplantation with antithymocyte globulin–based myeloablative conditioning in pediatric refractory or relapsed non‐Hodgkin lymphoma

Pediatric Investigation, EarlyView.
Single‐center retrospective data showed that ATG‐based myeloablative haploidentical hematopoietic stem cell transplantation provides durable remission and favorable long‐term survival in children with refractory/relapsed non‐Hodgkin lymphoma, achieving high engraftment rates, low relapse incidence, and acceptable toxicity.
Chenguang Jia, Jie Zheng, Meng Yuan, Hongbo He, Yibo Fan, Bin Wang, Guanghua Zhu, Jun Yang, Yanhui Luo, Lixiao Cai, Pan Zhang, Yanlong Duan, Maoquan Qin   +12 more
wiley   +1 more source

Phase disposition PWM control topology based: A novel multilevel inverter with reduced switch for power electronics applications. [PDF]

Heliyon
Y VS, R V.
europepmc   +1 more source

Modulation of wind drag by tidal currents in an embayment

Quarterly Journal of the Royal Meteorological Society, EarlyView.
Tidal currents modulate how wind energy enters the surface wave field by influencing both wave drag and wave generation. In Shark Bay, following currents reduce effective wave steepness and wind drag, and opposing currents enhance wave growth. Wind energy is partitioned between wave drag and the creation of new waves, explaining observed tidal ...
Stephen M. Thurgate, Michael V. W. Cuttler   +1 more
wiley   +1 more source

Androgen Receptor Drives Polyamine Synthesis, Creating a Vulnerability for Prostate Cancer. [PDF]

Cancer Res
Kumar R, Jonnatan S, Sanin DE, Vakkala V, Kadam A, Kumar S, Rosen DM, Dalrymple SL, Zhao L, Foley JR, Holbert CE, Nwafor A, Kittane S, Penner E, Apostolova P, Warner S, Dang CV, Toska E, Thompson EA, Isaacs JT, De Marzo AM, Brennen WN, Pearce EL, Stewart TM, Casero RA, Denmeade SR, Sena LA.   +26 more
europepmc   +1 more source