Results 261 to 270 of about 4,284,109 (332)

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Measuring the Quality of Species List Contents. [PDF]

Bioscience
Pape T, Pyle RL, Bánki O, Barik SK, Berryman AJ, Bouchard P, Buckeridge J, Christidis L, Cigliano MM, Conix S, Crawford-Weaver H, van Dijk PP, Döring M, Evenhuis N, Hilton-Taylor C, Hobern D, Johnston C, Klopper RR, Kroh A, Le Roux M, Lien AM, Raz L, Thomson S, Vandepitte L, Zachos FE, Garnett ST.   +25 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

The Cyprus Database of Alien Species (CyDAS). [PDF]

Sci Data
Demetriou J, Martinou AF, Bowler D, Peyton J, Pescott OL, Michailidis N, Mountford O, Onete M, Stoumboudi M, Rathod B, van Breda J, Roy HE, Zenetos A.   +12 more
europepmc   +1 more source

Metabolite names and identifiers: how far are we from interoperability? [PDF]

Metabolomics
Hajjar G, Giacomoni F, Umec M, Lefebvre M, Pimentel MPC, Prigent S, Cabasson C, Chagoyen M, Pétriacq P, Comte B, Pujos-Guillot E.   +10 more
europepmc   +1 more source

An Open Dataset of Chinese Name-to-Gender Associations for Gender Prediction in Broad Scientific Research. [PDF]

Sci Data
Shi D, Tong ST.
europepmc   +1 more source

A dataset of insect sounds from 459 species for bioacoustic machine learning. [PDF]

Sci Data
Faiß M, Ghani B, Stowell D.
europepmc   +1 more source

Experimental exposure to climate change scenarios imposed alterations on the morphological traits of sessile and low-motility marine invertebrates. [PDF]

Biodivers Data J
Chatzinikolaou E, Keklikoglou K, Vernadou E, Dailianis T.   +3 more
europepmc   +1 more source