Comparative efficacy of antidepressants for acute adolescent major depressive disorder: a source-verified systematic review and network meta-analysis. [PDF]
Gong C, Zeng W, Xiao X, Liu Q, Luo Y.
europepmc +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Mrs. Joseph E. Cockrell at Home to Standard Club
The program for the Standard Club event at the home of Mrs. Joseph E.
Standard Club of Dallas
core
Strengthening District- and Regional-Level Supportive Supervision for Facility HMIS Data Quality and Data Use in Somalia: A Healthcare Leadership Commentary. [PDF]
Osman NH +9 more
europepmc +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Impact of Mandatory Price Reporting on Fed Cattle Market Integration [PDF]
Geographic fed cattle markets are important because cattle are bulky and perishable, and production and consumption areas are separated. These characteristics make cattle transportation costly and can contribute to segmented markets. This study uses USDA-
Schroeder, Ted C., Pendell, Dustin L.
core
Industry payments and auditability of financial conflicts of interest in US gastroenterology and hepatology clinical practice guidelines: a cross-sectional analysis. [PDF]
Rodriguez SH +4 more
europepmc +1 more source
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Editorial: Reporting baseline variables - descriptive summaries rather than inferential comparisons: editorial series on improving reporting and methodological rigor in scientific articles. [PDF]
Christensen R +3 more
europepmc +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source

