Results 141 to 150 of about 2,427 (307)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Alternatives to sustainable development: what can we learn from the pluriverse in practice? [PDF]
Sustain Sci, 2022 Kaul S, Akbulut B, Demaria F, Gerber JF.
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Commoning as a postcapitalist politics
, 2016 Today the planet faces a genuine tragedy of the unmanaged ‘commons’. For decades an open access and unmanaged resource has been treated with the same sort of disregard as Hardin’s pasture was treated.
Gibson, Katherine (R14286) +2 more
core
Commoning Cosmopolitanism: Solidarity Beyond Capital, Borders, and Sameness
Social InclusionApproaches to situated and located cosmopolitanism offer the opportunity to think of the formation of a universal community, which demands equality and social justice and is rooted in urban and local practices.
Óscar García Agustín +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Welcome to Commoning Ethnography
, 2018 What does it mean to suggest that ethnography might be a site, source, or scene of commoning? What does combining the idea of commoning with the practice of ethnography allow us to think about or to do that we might not otherwise?
Elinoff, Eli, Trundle, Catherine
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The Seeds of The Commons: Peer-to-Peer Alternatives for Planetary Survival and Justice. [PDF]
Postdigit Sci Educ, 2021 Bauwens M, Jandrić P.
europepmc +1 more source