Results 61 to 70 of about 432,765 (298)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Common Transversals [PDF]

open access: yesProceedings of the Edinburgh Mathematical Society, 1966
A well-known theorem in group theory [(8), p. 11, Satz 3] asserts that, whenHis a subgroup of finite index in a groupG, there exists a system of common representatives of the right cosets and the left cosets ofHinG. Various proofs and generalisations, mainly involving combinatorial rather than grouptheoretical ideas, are known, and an excellent account
openaire   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Challenges in Expanding the Commonsverse

open access: yesInternational Journal of the Commons
Over the past two decades, hundreds of different commons around the world have arisen and developed working ties with peers, creating what might be called the Commonsverse.
David Bollier
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Common Bean

open access: yes, 2015
[EN] The common bean (Phaseolus vulgaris L.) is a diploid annual species and is predominantly self-pollinating. Common bean consists of two major gene pools, Mesoamerican and Andean, characterized by partial reproductive isolation, that include wild populations and cultivated varieties.
Ron, Antonio M. de   +14 more
openaire   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Probing Contextual Language Models for Common Ground with Visual\n Representations [PDF]

open access: green, 2020
Gabriel Ilharco   +3 more
openalex   +1 more source

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