Results 241 to 250 of about 3,265,734 (307)

Paracrine signals from HIV-1-infected immune cells reprogram cervical cancer pathways. [PDF]

iScience
Olwal CO, Rathore U, Makanani SK, Kaushal P, Ashley IA, Ummadi MR, Appiah V, Djomkam Zune AL, Blanc SF, Winters DM, Delgado Y, Muthoka K, Fabius JM, Eckhardt M, Kaake RM, Su M, Fregoso OI, Hultquist JF, Orang'o EO, Swaney DL, Kyei GB, Krogan NJ, Quashie PK, Bediako Y, Bouhaddou M.   +24 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

A cross-sectional study of the use of graduated compression stockings at two top end hospitals in Darwin, Australia. [PDF]

J Vasc Surg Venous Lymphat Disord
Byrnes JM, Commons RJ, Hamilton MJ, Bowden J, Ton T, Tole DT, Quader S, Wang Y, Vincent S, Jenkins L, Lu M, Wong J, Yun R, Sun J, Gordon A, McCallum GB.   +15 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Onchocerciasis elimination mapping in Malawi: mapping of vector Simulium breeding sites using an integrated approach of community knowledge and topographical maps. [PDF]

Int Health
Atekem K, Sitima L, Pemba D, Oumar AM, Isake B, Gowelo S, Chipatso C, Muheka K, Ayisi F, Koala L, Surakat O, Elaagip A, de Souza DK, Heggen A, Mackenzie CD, Boakye DA.   +15 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Novel Electronic Health Record-Based Data Commons for Pancreatic Cancer. [PDF]

JCO Clin Cancer Inform
Ahmed KS, Marcinak CT, Ali MM, Issaka SM, Yan Y, McMahan G, Callaci T, LoConte NK, Shiefelbein A, Weber S, Afshar M, Churpek MM, Mathew J, Zafar SN.   +13 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Optically addressable molecular spin qubits. [PDF]

MRS Bull
Mann SK, Bayliss SL.
europepmc   +1 more source

An evolutionary shift to prioritizing mating over care is associated with consistently high androgen levels in male threespine stickleback. [PDF]

Horm Behav
Maciejewski MF, Bell AM.
europepmc   +1 more source