Results 51 to 60 of about 298,278 (302)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Progress in human development: Are we on the right path? [PDF]

open access: yes
The conventional measure of Human Development Index (HDI) is a linear average across dimensions, HDI1. Under this, poor attainments in any dimension gets perfectly compensated for better attainments in any other dimension HDI2, which is based on ...
Hippu Salk Kristle Nathan, Srijit Mishra
core   +3 more sources

Death Rate as a Demo-economic Factor of the Country's Labour Potential Reduction [PDF]

open access: yes, 2016
The article deals with the impact of mortality rate on the reduction of labour potential. The authors determine the index of years of potential life lost, analyze the primary causes of deaths as well as provide some prognostic estimates concerning the ...
Kobelia, Z. (Zoryana)   +2 more
core  

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Institutional Regulation of the CIS Observer Mission in Election Campaigns and Coverage of Its Activities in the Media

open access: yesЕвразийская интеграция: экономика, право, политика
This study is aimed at studying the institutional, organizational and legal problems of interaction between the media and international observers during elections and referendums in the member states of the Commonwealth of Independent States.
S. A. Malinina
doaj   +1 more source

THE COMMONWEALTH OF INDEPENDENT STATES: DECAYED WITHIN A DECADE

open access: yesMilletleraras, 1998
The Commonwealth of Independent States (CIS) is an international organisation comprised of 12 sovereign states of former-Soviet Union. The genesis of the CIS dates back to 8 December 1991, thus 2001 heralded the tenth anniversary of this sui generis organisation.
openaire   +3 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Justice and constitutional and legal bases of civil proceedings in the countries of Commonwealth of independent states

open access: yesХабаршы. Заң сериясы, 2015
Some questions on constitutional­law bases of civil proceeding of Community of Independent States are considered in this article. In the Commonwealth countries of the independent states there are general regularities of development
Atakhanova S.K.
doaj  

"The Economic and Financial Crises in CEE and CIS: Gender Perspectives and Policy Choices" [PDF]

open access: yes
This paper looks at the countries of Central and Eastern Europe (CEE) and the Commonwealth of Independent States (CIS), where economies have been most dramatically hit by the global crisis and its impact is likely to be most long-lasting, especially ...
Fatma Gul Unal   +2 more
core  

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